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Amikacin Sulphate

CAS 149022-22-0: Amikacin Sulphate

Description:Amikacin sulfate is an aminoglycoside antibiotic primarily used to treat serious infections caused by Gram-negative bacteria. It is a semi-synthetic derivative of kanamycin and exhibits a broad spectrum of antibacterial activity, particularly against strains resistant to other aminoglycosides. The compound is typically administered via injection and is known for its effectiveness in treating infections such as pneumonia, sepsis, and urinary tract infections. Amikacin sulfate works by inhibiting bacterial protein synthesis, ultimately leading to cell death. Its pharmacokinetics include good tissue penetration, with a relatively long half-life compared to other aminoglycosides, allowing for less frequent dosing. However, it is important to monitor renal function during treatment, as nephrotoxicity is a potential side effect. Additionally, ototoxicity can occur, particularly with prolonged use or higher doses. Overall, amikacin sulfate is a valuable therapeutic agent in the arsenal against multidrug-resistant bacterial infections, but its use must be carefully managed to minimize adverse effects.

Formula:C22H45N5O17S

InChI:InChI=1/C22H43N5O13.H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;/m0./s1

  • Synonyms:
  • Amikacin Sulfate
  • Amikacin Disulfate Salt
  • 4-Amino-N-[5-Amino-2-[4-Amino-3,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydropyran-2-Yl]Oxy-4-[6-(Aminomethyl)-3,4,5-Trihydroxy-Tetrahydropyran-2-Yl]Oxy-3-Hydroxy-Cyclohexyl]-2-Hydroxy-Butanamide Disulfate Salt
  • 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)
  • (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide sulfate (salt)
  • Amikacin Sulfate Salt
  • (2R)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-α-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-α-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide sulfate (salt)
  • (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide sulfate (1:2)
  • Amikacin Sulfate 1:1.8
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Amikacin sulfate

CAS:149022-22-0

Ref: TM-T3125

10mg35.00 €
25mg46.00 €
50mg52.00 €
100mg52.00 €
Estimated delivery in United States, on Thursday 13 Mar 2025
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Ref: IN-DA001LCO

1g38.00 €
5g98.00 €
25g161.00 €
100g300.00 €
Estimated delivery in United States, on Thursday 13 Mar 2025
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Amikacin sulfate salt

CAS:149022-22-0

Ref: 7W-GA9402

1g149.00 €
5g463.00 €
Estimated delivery in United States, on Friday 14 Mar 2025
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Amikacin Sulfate RS

CAS:149022-22-0

Ref: 2K-7000040021

120mgTo inquire
Estimated delivery in United States, on Friday 21 Mar 2025
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