CAS 1491-59-4

Oxymetazoline

Description:

Oxymetazoline is a sympathomimetic amine primarily used as a topical decongestant. It acts as an alpha-adrenergic agonist, leading to vasoconstriction in the nasal mucosa, which reduces swelling and congestion. This compound is commonly found in over-the-counter nasal sprays and eye drops, providing relief from nasal congestion due to colds, allergies, or sinusitis. Oxymetazoline is characterized by its relatively rapid onset of action and prolonged duration of effect, making it effective for short-term use. However, prolonged use can lead to rebound congestion, a phenomenon known as rhinitis medicamentosa. The substance is typically administered in low concentrations, and its safety profile is well-established, although side effects may include local irritation or dryness. Chemically, oxymetazoline is a derivative of imidazoline, and its structure includes a phenolic hydroxyl group, contributing to its pharmacological activity. As with any medication, it is important to follow dosing guidelines to minimize potential adverse effects.

Formula: C₁₆H₂₄N₂O

InChI: InChI=1/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H

InChI key: InChIKey=WYWIFABBXFUGLM-UHFFFAOYSA-N

SMILES: C(C1=C(C)C(O)=C(C(C)(C)C)C=C1C)C=2NCCN2

Synonyms:

• 2-(4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
• 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
• 6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
• Hazol
• Navasin
• Navisin
• Nezeril
• Oximetazolina
• Oxylazine
• Oxymetazolin
• Oxymetazoline
• Oxymethazoline
• Phenol, 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-
• Rhinofrenol
• Rhinolitan
• Sinerol
• Phenol, 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-
• 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-xylenol
• 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol hydrochloride (1:1)
• 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
• H-990
• h990
• Nafrine
• 6-t-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
• Iliadin
• 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-pheno
• afrin
• nasivin
• Nasivine

Oxymetazoline

CAS: 1491-59-4

Formula: C₁₆H₂₄N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 260.3746

Ref: IN-DA001LE8

Oxymetazoline

CAS: 1491-59-4

Formula: C₁₆H₂₄N₂O

Color and Shape: White To Off-White Solid

Molecular weight: 260.38

Ref: 4Z-O-029001

Oxymetazoline Hydrochloride

CAS: 1491-59-4, 2315-02-8

Formula: C₁₆H₂₄N₂O·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 296.84

Ref: 3B-O0520

OxyMetazoline

CAS: 1491-59-4

OxyMetazoline: α-adrenoceptor agonist, relieves nasal congestion, targets α1A, α1B, α2A, α2C.

Formula: C₁₆H₂₄N₂O

Color and Shape: Solid

Molecular weight: 260.37

Ref: TM-T64314