CAS 14918-35-5

destomycin A

Description:

Destomycin A is a natural antibiotic compound that belongs to the class of polyketides. It is produced by certain strains of the bacterium Streptomyces, which are known for their ability to synthesize a wide variety of bioactive secondary metabolites. Destomycin A exhibits notable antibacterial properties, particularly against Gram-positive bacteria, making it of interest in the field of medicinal chemistry and antibiotic development. The compound is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its biological activity. Its mechanism of action typically involves interference with bacterial cell wall synthesis or function, although specific pathways may vary. Additionally, destomycin A has been studied for its potential applications in cancer therapy due to its cytotoxic effects on certain tumor cell lines. As with many natural products, the extraction and purification of destomycin A can be challenging, and ongoing research aims to explore its full therapeutic potential and to develop synthetic analogs that may enhance its efficacy and reduce toxicity.

Formula: C₂₀H₃₇N₃O₁₃

InChI: InChI=1/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6?,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20-/m1/s1

InChI key: InChIKey=GRRNUXAQVGOGFE-SVNOMHMPSA-N

SMILES: O[C@H]1C2(O[C@]3([C@@](O2)([C@@H](O)[C@@H](CO)O[C@H]3O[C@@H]4[C@@H](O)[C@H](NC)C[C@H](N)[C@H]4O)[H])[H])O[C@]([C@H](CO)N)([C@H](O)[C@@H]1O)[H]

Synonyms:

• (3'R,3aS,4S,4'S,5'R,6R,6'R,7S,7aS)-4-{[(1S,2R,3S,5R,6S)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)octahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-3',4',5',7-tetrol (non-preferred name)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-6-amino-6-deoxy-<smallcap>L</smallcap>-glycero-<smallcap>D</smallcap>-galacto-heptopyranosylidene-(1→2-3)-O-β-<smallcap>D</span>-talopyranosyl-(1→5)-2-deoxy-N¹-methyl-
• Destonate 20
• Destonmycin A
• NSC 96877
• O-6-Amino-6-deoxy-<span class="text-smallcaps">L</smallcap>-glycero-<smallcap>D</smallcap>-galacto-heptopyranosylidene-(1→2-3)-O-β-<smallcap>D</smallcap>-talopyranosyl-(1→5)-2-deoxy-N¹-methyl-<smallcap>D</span>-streptamine
• Spiro[4H-1,3-dioxolo[4,5-c]pyran-2,2′-[2H]pyran], <span class="text-smallcaps">D</span>-streptamine deriv.
• O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1→2-3)-O-β-D-talopyranosyl-(1→5)-2-deoxy-N1-methyl-D-streptamine
• Destomycin A
• D-Streptamine, O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1→2-3)-O-β-D-talopyranosyl-(1→5)-2-deoxy-N1-methyl-
• Spiro[4H-1,3-dioxolo[4,5-c]pyran-2,2′-[2H]pyran], D-streptamine deriv.
• 5)-2-deoxy-N1-methyl-
• DestoMycin
• 2-3)-O-b-D-talopyranosyl-(1&reg
• destomycin A USP/EP/BP
• D-Streptamine,O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1&reg

Destomycin A

CAS: 14918-35-5

Destomycin A, an aminoglycoside antibiotic, exhibits activity against bacterial (Gram-positive and Gram-negative), antifungal, and anthelmintic agents. It inhibits peptide synthesis in Escherichia coli cells and stimulates adenylate cyclase in animal tissues.

Formula: C₂₀H₃₇N₃O₁₃

Color and Shape: Solid

Molecular weight: 527.52

Ref: TM-TN8311

Destomycin A

CAS: 14918-35-5

Destomycin A is an antibiotic, which is derived from the bacterium Streptomyces species. This compound exhibits a broad-spectrum mode of action by inhibiting protein synthesis in bacterial cells, thus impeding their growth and proliferation. Destomycin A targets the ribosomal subunits within bacterial cells, leading to disruption in their ability to synthesize essential proteins, ultimately contributing to its bacteriostatic effects.

Formula: C₂₀H₃₇N₃O₁₃

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 527.52 g/mol

Ref: 3D-FD166104