CAS 14919-77-8: Benserazide hydrochloride

Description: Benserazide hydrochloride is a pharmaceutical compound primarily used as a peripheral decarboxylase inhibitor in the treatment of Parkinson's disease. It is often administered in combination with levodopa to enhance the latter's efficacy by preventing its conversion to dopamine outside the central nervous system, thereby increasing its availability in the brain. This compound is characterized by its white to off-white crystalline appearance and is soluble in water, which facilitates its formulation in various dosage forms. The molecular structure of benserazide includes a hydrazine moiety, contributing to its pharmacological activity. Its mechanism of action involves the inhibition of the enzyme aromatic L-amino acid decarboxylase, which is crucial for the metabolism of levodopa. Benserazide hydrochloride is typically well-tolerated, but like all medications, it may have side effects, including gastrointestinal disturbances and potential interactions with other drugs. Proper dosage and administration are essential to maximize therapeutic benefits while minimizing adverse effects.

Formula: C₁₀H₁₅N₃O₅·ClH

InChI: InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H

InChI key: InChIKey=ULFCBIUXQQYDEI-UHFFFAOYSA-N

SMILES: Cl.O=C(NNCC1=CC=C(O)C(O)=C1O)C(N)CO

Synonyms:

• (S)-2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
• 2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
• <span class="text-smallcaps">DL</span>-Serine N²-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
• <span class="text-smallcaps">DL</span>-Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, monohydrochloride
• Benserazide Hcl
• DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
• N-(<span class="text-smallcaps">DL</span>-Seryl)-N′-(2,3,4-trihydroxybenzyl)hydrazine hydrochloride
• Ro 4-4602
• Ro 4-4602/001
• Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, monohydrochloride
• Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, hydrochloride (1:1)
• Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, monohydrochloride
• DL-Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, monohydrochloride
• N-(DL-Seryl)-N′-(2,3,4-trihydroxybenzyl)hydrazine hydrochloride

Benserazide Hydrochloride

CAS: 14919-77-8322-35-0

• Formula: C₁₀H₁₅N₃O₅·HCl
• Purity: >97.0%(T)(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 293.70

Benserazide hydrochloride

CAS: 14919-77-8

Inhibitor of L-aromatic amino acid decarboxylaseBenserazide hydrochloride is used as an antiparkinsonian. It is a …

• Formula: C₁₀H₁₅N₃O₅•HCl
• Molecular weight: 293.7

BENSERAZIDE HYDROCHLORIDE CRS

CAS: 14919-77-8

• Formula: C₁₀H₁₆ClN₃O₅
• Color and Shape: Crystalline Powder. White. Yellow. Orange. Powder.
• Molecular weight: 293.7041

Benserazide for peak identification A CRS

CAS: 14919-77-8

Benserazide hydrochloride

CAS: 14919-77-8

Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.

• Formula: C₁₀H₁₅N₃O₅·HCl
• Purity: 98.63% - 99.74%
• Color and Shape: White Crystalline Solid
• Molecular weight: 293.7

Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, hydrochloride (1:1)

CAS: 14919-77-8

• Formula: C₁₀H₁₆ClN₃O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 293.7041

Benserazide hydrochloride

CAS: 14919-77-8

• Purity: 98%
• Molecular weight: 293.7g/mol

Benserazide hydrochloride

CAS: 14919-77-8

• Purity: ≥98%
• Molecular weight: 293.7g/mol

Benserazide hydrochloride

CAS: 14919-77-8

• Formula: C₁₀H₁₅N₃O₅·HCl
• Purity: 98.0 - 101.0 % (dried basis)
• Color and Shape: White, off-white or faint yellow-orange powder
• Molecular weight: 293.70

Benserazide-d3 HCl

CAS: 14919-77-8

• Formula: C₁₀H₁₂D₃N₃O₅·HCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 260.27 36.46

Benserazide HCl

CAS: 14919-77-8

• Formula: C₁₀H₁₅N₃O₅·HCl
• Color and Shape: Off-White Solid
• Molecular weight: 257.25 36.46

BENSERAZIDE HYDROCHLORIDE

CAS: 14919-77-8

• Purity: 95%
• Molecular weight: 293.700012207031

Benserazide Hydrochloride

CAS: 14919-77-8

• Formula: C₁₀H₁₅N₃O₅·ClH
• Color and Shape: Neat
• Molecular weight: 293.70

Benserazide-d3 Hydrochloride

CAS: 14919-77-8

Applications Used as antiparkinsonian. A peripheral decarboxylase inhibitor. References Burkard, W.P., et al.: Experientia, 18, …

• Formula: C₁₀H₁₃D₃ClN₃O₅
• Color and Shape: Neat
• Molecular weight: 296.72

(S)-2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride

CAS: 14919-77-8

• Purity: 95.0%
• Molecular weight: 293.70001220703125

Benserazide Hydrochloride

CAS: 14919-77-8

• Formula: C₁₀H₁₅N₃O₅·ClH
• Color and Shape: White To Off-White
• Molecular weight: 293.70

Benserazide HCl - Bio-X ™

CAS: 14919-77-8

Benserazide is a drug that is used for the treatment of Parkinson’s disease and restless …

• Formula: C₁₀H₁₅N₃O₅•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 293.7 g/mol

Benserazide hydrochloride

CAS: 14919-77-8

Dopamine decarboxylase inhibitor

• Formula: C₁₀H₁₆ClN₃O₅
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 293.7 g/mol