CAS 149231-65-2

N-acetyl-tyr-val-ala-asp 7-amido-4-*methylcoumari

Description:

N-acetyl-tyr-val-ala-asp 7-amido-4-methylcoumarin, identified by its CAS number 149231-65-2, is a synthetic compound that belongs to the class of peptide derivatives. This substance features a combination of amino acids, specifically N-acetyltyrosine, valine, alanine, and aspartic acid, linked together in a specific sequence. The presence of the 7-amido-4-methylcoumarin moiety suggests that it has fluorescent properties, making it useful in biochemical assays and research applications, particularly in studying enzyme activity or protein interactions. The N-acetyl group enhances its solubility and stability, while the coumarin component can serve as a reporter group in various analytical techniques. Overall, this compound is characterized by its peptide structure, potential bioactivity, and utility in fluorescence-based applications, contributing to its relevance in biochemical and pharmaceutical research.

Formula: C₃₃H₃₉N₅O₁₀

Synonyms:

• Ac-Yvad-Amc

Ac-Tyr-Val-Ala-Asp-AMC

CAS: 149231-65-2

Ac-YVAD-AMC is a fluorogenic substrate for caspase-1 (ICE). It displayed a Km of 8.5 ± 0.5 µM for recombinant human caspase-1.

Formula: C₃₃H₃₉N₅O₁₀

Purity: 99.3%

Color and Shape: White Powder

Molecular weight: 665.7

Ref: 01-4017748

N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-methylcoumarin

CAS: 149231-65-2

Formula: C₃₃H₃₉N₅O₁₀

Molecular weight: 665.69

Ref: 7W-GK6665

Ac-Tyr-Val-Ala-Asp-AMC

CAS: 149231-65-2

Ac-Tyr-Val-Ala-Asp-AMC is a peptide that is used as a research tool to activate ion channels in cells and study the effects of ligands on these channels. It is also used in cell biology to study protein interactions, although it does not bind to any specific receptor. Ac-Tyr-Val-Ala-Asp-AMC belongs to the group of inhibitors and can be used for pharmacological purposes. The chemical structure of this peptide consists of a covalent bond between an amino acid and an acetylated form of a fluorescent molecule, which makes it suitable for use in fluorescence microscopy. Acetylated Tyr (Ac-Tyr) is one of the six amino acids found in proteins and has the ability to inhibit the activity of ion channels by binding to their external cavity. Acetylation at position 2 or 3 on Tyr can increase its affinity for calcium ion channels and affect their activation or de

Formula: C₃₃H₃₉N₅O₁₀

Purity: Min. 95%

Molecular weight: 665.69 g/mol

Ref: 3D-MAY-3161-V

Ac-Tyr-Val-Ala-Asp-AMC

CAS: 149231-65-2

Ac-Tyr-Val-Ala-Asp-AMC is a compound that has been shown to induce apoptotic cell death in MDA-MB-231 breast cancer cells. It inhibits the activity of proteases, which are enzymes that degrade proteins. Ac-Tyr-Val-Ala-Asp-AMC has also been shown to inhibit serine proteases and granule neurons, which are proteins in the brain that regulate the production of atp levels. Ac-Tyr-Val-Ala-Asp-AMC has also been shown to inhibit muscle cell proliferation. Acetylcholine (ACh) is a neurotransmitter responsible for signaling between nerve cells in the central nervous system and other parts of the body. Acetylcholine is synthesized by choline acetyltransferase (ChAT), an enzyme that breaks down acetylcholine into choline and acetate. Inhibition of ChAT leads to a decrease in

Formula: C₃₃H₃₉N₅O₁₀

Purity: Min. 95%

Molecular weight: 665.69 g/mol

Ref: 3D-FA110563