CAS 149281-19-6

1H-Indeno[5,4-f]quinoline-7-carboxamide,N-(1-cyano-1-methylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-,(4aR,4bS,6aS,7S,9aS,9bS,11aR)-

Description:

1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1-cyano-1-methylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)- is a complex organic compound characterized by its unique bicyclic structure, which incorporates both indeno and quinoline moieties. This compound features multiple stereocenters, contributing to its chiral nature, which can influence its biological activity and interactions. The presence of a carboxamide functional group suggests potential for hydrogen bonding, enhancing solubility in polar solvents. Additionally, the cyano and dimethyl groups may impart specific electronic properties, affecting reactivity and stability. The tetradecahydro structure indicates a saturated framework, which may contribute to its rigidity and conformational stability. Overall, this compound's intricate structure and functional groups suggest potential applications in pharmaceuticals or materials science, although specific biological or chemical properties would require further investigation through experimental studies.

Formula: C₂₃H₃₃N₃O₂

Synonyms:

• 4-Azaandrost-1-ene-17-carboxamide,N-(1-cyano-1-methylethyl)-3-oxo-, (5a,17b)-
• 1H-Indeno[5,4-f]quinoline-7-carboxamide,N-(1-cyano-1-methylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-,[4aR-(4aa,4bb,6aa,7a,9ab,9ba,11ab)]-
• Cgp 53153

CGP-53153

CAS: 149281-19-6

CGP-53153 is a steroidal inhibitor of 5 alpha-reductase (IC50s: 36 and 262 nM in rat and human prostatic tissue).

Formula: C₂₃H₃₃N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 383.53

Ref: TM-T10780

CGP-53153

CAS: 149281-19-6

CGP-53153 is an inhibitor of the protein tyrosine phosphatase SHP2. The inhibition of SHP2 by CGP-53153 has been shown to result in increased proliferation of human breast cancer cells. This drug is a small molecule that binds to the SHP2 receptor, and blocks its activation by phosphatidylinositol 3,4,5-trisphosphate (PIP3). CGP-53153 is a ligand for the SHP2 receptor and can be used as a research tool to study protein interactions.

Formula: C₂₃H₃₃N₃O₂

Purity: Min. 95%

Molecular weight: 383.5 g/mol

Ref: 3D-ZFA28119