CymitQuimica logo

CAS 14929-11-4

:

simfibrate

Description:
Simfibrate is a chemical compound classified as a fibrate, primarily used in the management of dyslipidemia, particularly to lower triglyceride levels and increase high-density lipoprotein (HDL) cholesterol. It is known for its lipid-modifying properties, functioning as a peroxisome proliferator-activated receptor (PPAR) agonist, which enhances fatty acid oxidation and reduces triglyceride synthesis in the liver. The compound typically appears as a white to off-white crystalline powder and is soluble in organic solvents but has limited solubility in water. Simfibrate is often administered in conjunction with dietary modifications to achieve optimal lipid profiles. Its pharmacokinetics involve absorption from the gastrointestinal tract, with metabolism primarily occurring in the liver. While generally well-tolerated, potential side effects may include gastrointestinal disturbances and, in rare cases, liver enzyme elevations. As with any medication, it is essential to monitor patients for efficacy and adverse reactions during treatment.
Formula:C23H26Cl2O6
InChI:InChI=1/C23H26Cl2O6/c1-22(2,30-18-10-6-16(24)7-11-18)20(26)28-14-5-15-29-21(27)23(3,4)31-19-12-8-17(25)9-13-19/h6-13H,5,14-15H2,1-4H3
InChI key:InChIKey=JLRNKCZRCMIVKA-UHFFFAOYSA-N
SMILES:O(C(C(OCCCOC(C(OC1=CC=C(Cl)C=C1)(C)C)=O)=O)(C)C)C2=CC=C(Cl)C=C2
Synonyms:
  • 1,3-Propane bis(2-p-chlorophenoxy-2-methylpropanoate)
  • 1,3-Propanediol Bis[2-(4-chlorophenoxy)-2-methylpropionate]
  • 1,3-Propanediol Bis[a-(p-chlorophenoxy)isobutyrate]
  • 1,3-Propanediol bis(2-p-chlorophenoxyisobutyrate)
  • 1,3-Propanediol bis[α-(chlorophenoxy)isobutyrate]
  • 1,3-Propanediol, bis[2-(p-chlorophenoxy)-2-methylpropionate]
  • 1,3-Propanediyl bis(α-p-chlorophenoxyisobutyrate)
  • 1,3-Propanediyl bis[2-(4-chlorophenoxy)-2-methylpropanoate]
  • 14929-11-4
  • 2-(p-Chlorphenoxy)-2-methylpropionic acid trimethylene ester
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.