CAS 149394-66-1: Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, hydrate (1:2)

Description: Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, hydrate (1:2), identified by CAS number 149394-66-1, is a chemical compound characterized by its phosphonic acid functional group, which imparts significant acidity and reactivity. This compound features a pyrimidine derivative, contributing to its biological activity, particularly in pharmaceutical applications. The presence of the hydroxymethyl and ethoxy groups enhances its solubility and interaction with biological systems. As a hydrate, it contains water molecules in its structure, which can influence its stability and reactivity. The compound is likely to exhibit properties typical of phosphonic acids, such as chelation with metal ions and potential use as a herbicide or in medicinal chemistry. Its specific stereochemistry, indicated by the (1S) configuration, suggests that it may have distinct biological activity based on its three-dimensional arrangement. Overall, this compound's unique structure and functional groups make it of interest in various chemical and biological research fields.

Formula: C₈H₁₄N₃O₆P·2H₂O

InChI: InChI=1S/C8H14N3O6P.2H2O/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16;;/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16);2*1H2/t6-;;/m0../s1

InChI key: InChIKey=FPKARFMSZDBYQF-ILKKLZGPSA-N

SMILES: O=C1N=C(N)C=CN1CC(OCP(=O)(O)O)CO.O

Synonyms:

• ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid dihydrate
• Cidofovir hydrate
• Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, hydrate (1:2)
• Phosphonic acid, [[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, dihydrate
• Phosphonic acid, [[2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, dihydrate, (S)-
• acide {[(1S)-2-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-(hydroxyméthyl)éthoxy]méthyl}phosphonique dihydrate
• phosphonic acid, [[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, dihydrate
• {[(1S)-2-(4-Amino-2-oxopyrimidin-1(2H)-yl)-1-(hydroxymethyl)ethoxy]methyl}phosphons?uredihydrat
• {[(1S)-2-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-(hydroxymethyl)ethoxy]methyl}phosphonic acid dihydrate

Cidofovir

CAS: 149394-66-1

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

• Formula: C₈H₁₄N₃O₆P·2H₂O
• Color and Shape: White Off-White Powder
• Molecular weight: 315.08315

Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, hydrate (1:2)

CAS: 149394-66-1

• Formula: C₈H₁₈N₃O₈P
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 315.2176

(S)-(((1-(4-Amino-2-Oxopyrimidin-1(2H)-yl)-3-HydrOxypropan-2-yl)Oxy)Methyl)Phosphonic Acid Dihydrate

CAS: 149394-66-1

• Purity: 98%
• Molecular weight: 315.22g/mol

Cidofovir Dihydrate

CAS: 149394-66-1

• Formula: C₈H₁₄N₃O₆P·2H₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 315.22

Cidofovir dihydrate

CAS: 149394-66-1

Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in …

• Formula: C₈H₁₈N₃O₈P
• Purity: 99.44%
• Color and Shape: Solid
• Molecular weight: 315.22

Cidofovir dihydrate

CAS: 149394-66-1

Anti-viral; DNA polymerase inhibitor

• Formula: C₈H₁₄N₃O₆P•(H₂O)₂
• Purity: Min. 98 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 315.22 g/mol

Cidofovir dihydrate - Bio-X ™

CAS: 149394-66-1

Cidofovir is an anti-viral agent that is used to treat Cytomegalovirus (CMV) retinitis in patients …

• Formula: C₈H₁₄N₃O₆P•(H₂O)₂
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 315.22 g/mol