CAS 149404-21-7

Enalapril sodium

Description:

Enalapril sodium is a pharmaceutical compound primarily used as an antihypertensive agent in the treatment of high blood pressure and heart failure. It is an angiotensin-converting enzyme (ACE) inhibitor that works by relaxing blood vessels, thereby reducing blood pressure and improving blood flow. The substance is a white to off-white crystalline powder, soluble in water, and has a molecular formula that reflects its structure as a prodrug, which is converted into its active form, enalaprilat, in the body. Enalapril sodium is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include dizziness, headache, and gastrointestinal disturbances, while more serious risks involve potential kidney impairment and hyperkalemia. As with all medications, it is essential to use enalapril sodium under medical supervision to monitor for adverse effects and interactions with other drugs.

Formula: C₂₀H₂₈N₂O₅·Na

InChI: InChI=1S/C20H28N2O5.Na/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25;/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25);/t14-,16-,17-;/m0./s1

InChI key: InChIKey=CLDRAUZFKNARLS-BDURURIASA-N

SMILES: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)CCC2.[Na]

Synonyms:

• L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-, monosodium salt
• Enalapril sodium
• L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, monosodium salt, (S)-
• L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-, sodium salt (1:1)

Enalapril sodium

CAS: 149404-21-7

Enalapril sodium is used to treat high blood pressure, diabetic kidney disease, and heart failure and can be generally used with a diuretic such as furosemide

Formula: C₂₀H₂₈N₂NaO₅

Color and Shape: Solid

Molecular weight: 399.443

Ref: TM-T1605L