CAS 149488-17-5

trovirdine

Description:

Trovirdine is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of non-nucleoside reverse transcriptase inhibitors (NNRTIs), which function by inhibiting the reverse transcriptase enzyme, thereby preventing the replication of the virus. Trovirdine is characterized by its ability to bind to the reverse transcriptase enzyme, leading to a conformational change that inhibits its activity. The compound is typically administered orally and has a specific pharmacokinetic profile, including absorption, distribution, metabolism, and excretion characteristics that influence its efficacy and safety. While it has shown effectiveness in clinical settings, it is important to note that resistance can develop, necessitating careful monitoring and potential combination with other antiretroviral agents. As with many medications, potential side effects may include rash, gastrointestinal disturbances, and effects on liver function, making it essential for healthcare providers to evaluate the risk-benefit ratio for individual patients. Overall, Trovirdine represents a significant option in the ongoing fight against HIV/AIDS.

Formula: C₁₃H₁₃BrN₄S

InChI: InChI=1/C13H13BrN4S/c14-10-4-5-12(17-9-10)18-13(19)16-8-6-11-3-1-2-7-15-11/h1-5,7,9H,6,8H2,(H2,16,17,18,19)

SMILES: c1ccnc(c1)CCN=C(Nc1ccc(cn1)Br)S

Synonyms:

• Trovirdine [INN]
• 1-(5-Bromo-2-pyridyl)-3-(2-(2-pyridyl)ethyl)-2-thiourea
• Unii-Ze3K6J8614
• 1-(5-Bromopyridin-2-Yl)-3-(2-Pyridin-2-Ylethyl)Thiourea

Trovirdine

CAS: 149488-17-5

Formula: C₁₃H₁₃BrN₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 337.2381

Ref: IN-DA00ABLX

Trovirdine

CAS: 149488-17-5

Trovirdine

Purity: ≥98%

Molecular weight: 337.24g/mol

Ref: 54-BUP05832

Trovirdine

CAS: 149488-17-5

Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.

Formula: C₁₃H₁₃BrN₄S

Purity: 98.12% - 98.50%

Color and Shape: Solid

Molecular weight: 337.24

Ref: TM-T3172

TROVIRDINE

CAS: 149488-17-5

Purity: ≥98%

Molecular weight: 337.2399902

Ref: 10-F805023