CAS 149633-99-8

Jadomycin B

Description:

Jadomycin B is a naturally occurring antibiotic compound that belongs to the class of anthracycline antibiotics. It is produced by the fermentation of the bacterium *Streptomyces venezuelae*. This compound exhibits notable antibacterial and antitumor properties, making it of interest in pharmaceutical research. Jadomycin B is characterized by its complex polycyclic structure, which includes multiple aromatic rings and functional groups that contribute to its biological activity. The compound has been studied for its mechanism of action, which involves the inhibition of DNA synthesis in target cells, leading to cell death. Additionally, Jadomycin B has shown potential in overcoming resistance in certain bacterial strains, highlighting its significance in the development of new therapeutic agents. Its chemical properties, such as solubility and stability, are influenced by its molecular structure, which can affect its efficacy and application in medicinal chemistry. Overall, Jadomycin B represents a valuable compound in the ongoing search for effective antibiotics and anticancer therapies.

Formula: C₃₀H₃₁NO₉

InChI: InChI=1S/C30H31NO9/c1-5-13(3)24-30(37)40-29-16-9-12(2)10-17(32)21(16)23-25(31(24)29)28(36)22-15(27(23)35)7-6-8-19(22)39-20-11-18(33)26(34)14(4)38-20/h6-10,13-14,18,20,24,26,29,32-34H,5,11H2,1-4H3/t13-,14-,18+,20-,24-,26-,29?/m0/s1

InChI key: InChIKey=BSBSCJRAEMDCHC-LVOPHWFOSA-N

SMILES: [C@@H](CC)(C)[C@@]1(N2C3=C(C=4C(C2(OC1=O)[H])=CC(C)=CC4O)C(=O)C=5C(C3=O)=C(O[C@H]6C[C@@H](O)[C@@H](O)[C@H](C)O6)C=CC5)[H]

Synonyms:

• (1S,3aS)-1-[(2S)-butan-2-yl]-7-hydroxy-1,3a,5-trimethyl-2,8,13-trioxo-1,2,8,13-tetrahydro-3aH-benzo[b][1,3]oxazolo[3,2-f]phenanthridin-12-yl 2,6-dideoxy-alpha-L-ribo-hexopyranoside
• Jadomycin B
• 1-(butan-2-yl)-7-hydroxy-5-methyl-2,8,13-trioxo-1,2,8,13-tetrahydro-3aH-benzo[b][1,3]oxazolo[3,2-f]phenanthridin-12-yl 2,6-dideoxyhexopyranoside
• 8H-Benzo(b)oxazolo(3,2-f)phenanthridine-2,8,13(1H,3aH)-trione, 12-((2,6-dideoxyhexopyranosyl)oxy)-7-hydroxy-5-methyl-1-(1-methylpropyl)-
• 8H-Benz[b]oxazolo[3,2-f]phenanthridine-2,8,13(1H,3aH)-trione, 12-[(2,6-dideoxy-α-L-ribo-hexopyranosyl)oxy]-7-hydroxy-5-methyl-1-[(1S)-1-methylpropyl]-
• 12-[(2,6-Dideoxy-α-L-ribo-hexopyranosyl)oxy]-7-hydroxy-5-methyl-1-[(1S)-1-methylpropyl]-8H-benz[b]oxazolo[3,2-f]phenanthridine-2,8,13(1H,3aH)-trione

Jadomycin B

CAS: 149633-99-8

A jadomycin is an anacyclic natural product produced by Streptomyces venezuelae ISP5230.

Formula: C₃₀H₃₁NO₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 549.576

Ref: TM-T24190

Jadomycin B

Controlled Product

CAS: 149633-99-8

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Formula: C₃₀H₃₁NO₉

Purity: Min. 95%

Molecular weight: 549.6 g/mol

Ref: 3D-ZFA63399