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CAS 149732-51-4

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O-Demethylcurcumin

Description:
O-Demethylcurcumin is a synthetic derivative of curcumin, which is the active compound found in turmeric. This compound is characterized by its yellow-orange color and is known for its potential biological activities, including anti-inflammatory, antioxidant, and anticancer properties. O-Demethylcurcumin is structurally similar to curcumin but lacks one of the methoxy groups, which may influence its solubility and bioavailability. It is often studied for its pharmacological effects and mechanisms of action in various biological systems. The compound is soluble in organic solvents but has limited solubility in water, which can affect its application in biological studies. Research indicates that O-Demethylcurcumin may exhibit enhanced potency compared to curcumin in certain contexts, making it a subject of interest in medicinal chemistry and drug development. Its safety profile and therapeutic potential are still under investigation, highlighting the need for further studies to fully understand its effects and applications in health and disease.
Formula:C20H18O6
InChI:InChI=1S/C20H18O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)12-15(21)6-2-13-4-8-17(23)19(25)10-13/h2-11,23-25H,12H2,1H3/b6-2+,7-3+
InChI key:InChIKey=FFRFJIZJLZXEJX-YPCIICBESA-N
SMILES:C(=C/C(CC(/C=C/C1=CC(O)=C(O)C=C1)=O)=O)\C2=CC(OC)=C(O)C=C2
Synonyms:
  • O-Demethylcurcumin
  • 1,6-Heptadiene-3,5-dione, 1-(3,4-dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-, (E,E)-
  • Monodemethylcurcumin
  • 1,6-Heptadiene-3,5-dione, 1-(3,4-dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-
  • (1E,6E)-1-(3,4-Dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
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Found 3 products.
  • CymitQuimica logo
    TRC
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    Demethyl Curcumin

    CAS:
    Formula:C20H18O6

    Ref: TR-TRC-D230865

    25mg
    To inquire
    100mg
    To inquire
    50mg
    288.00€
  • Demethyl Curcumin
    TRC
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    Demethyl Curcumin

    Controlled Product
    CAS:

    Applications A metabolite of Curcumin (C838500) with potent activity against Trypanosoma and Leishmania species.
    References Asai, A., et al.: Life Sci., 67, 2785 (2000), Sharma, R., et al.: Eur. J. Cancer, 41, 1955 (2005), King, R., et al.: Curr. Drug Metab., 7, 541 (2006),

    Formula:C20H18O6
    Color and Shape:Neat
    Molecular weight:354.35

    Ref: TR-D230865

    25mg
    180.00€
    50mg
    296.00€
    100mg
    511.00€
  • Demethyl curcumin
    Biosynth
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    Demethyl curcumin

    CAS:

    Curcumin is a natural compound that has been shown to have anti-inflammatory, antioxidant, and anticancer properties. Curcumin is an active ingredient in the spice turmeric, which has been used for centuries in Indian cooking and traditional medicine. Demethyl curcumin (DMC) is a synthetic analog of curcumin that is modified by removing the methyl group on the aromatic ring. DMC has been shown to promote axonal growth and suppress inflammation in vitro, although it has not yet been tested in vivo. DMC also binds to epidermal growth factor receptors with high affinity but low efficacy. The site specificity of this binding may be due to hydroxyl groups on the curcumin molecule or other structural features. It also inhibits inflammatory bowel disease by inhibiting NF-κB activation.

    Formula:C20H18O6
    Purity:Min. 95 Area-%
    Color and Shape:Powder
    Molecular weight:354.35 g/mol

    Ref: 3D-FD20992

    50mg
    869.00€
    100mg
    1,021.00€