CAS 14976-57-9
:Clemastine fumarate
Description:
Clemastine fumarate is an antihistamine medication primarily used to relieve allergy symptoms, such as runny nose, sneezing, and itching. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, often leading to sedative effects. The substance is a salt formed from clemastine, a diphenylmethanol derivative, and fumaric acid. In its pure form, clemastine fumarate appears as a white to off-white crystalline powder, which is soluble in water and alcohol. Its mechanism of action involves antagonizing the H1 histamine receptors, thereby inhibiting the effects of histamine, a compound involved in allergic responses. Additionally, clemastine fumarate may exhibit anticholinergic properties, contributing to its efficacy in alleviating symptoms. The compound is typically administered orally and is available in various formulations, including tablets and syrups. As with many antihistamines, potential side effects may include drowsiness, dry mouth, and dizziness, necessitating caution when driving or operating heavy machinery.
Formula:C21H26ClNO·C4H4O4
InChI:InChI=1/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2;5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t20-,21-;/m1./s1
SMILES:[C@@](OCC[C@@H]1N(C)CCC1)(C)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3.C(=C/C(O)=O)\C(O)=O
Synonyms:- (+)-(2R)-2-[2-[[(R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine
- (+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate
- (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy)]Ethyl]-1-Methyl-2-Pyrrolidine Fumarate
- (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine
- (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine (2E)-but-2-enedioate
- 2-{2-[1-(4-Chlorophenyl)-1-Phenylethoxy]Ethyl}-1-Methylpyrrolidine
- Agasten
- Aloginan
- Alphamin
- Anhistan
- Bravegyl
- Clemastine
- Clemastine Fumarate Salt
- Clemastine Hydrogen Fumarate
- Clemastinum
- Fuluminol
- Hs 592
- Inbestan
- Kinotomin
- Lacretin
- Lecasol
- Maikohis
- Mallermin F
- Marsthine
- Masletine
- Meclastine fumarate
- Mecloprodine
- Piloral
- Pyrrolidine, 2-2-(1R)-1-(4-chlorophenyl)-1-phenylethoxyethyl-1-methyl-, (2R)-
- Pyrrolidine, 2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, (2R)-, (2E)-2-butenedioate (1:1)
- Pyrrolidine, 2-[2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methyl-, (+)- (8CI)
- Pyrrolidine, 2-[2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methyl-, (+)-, fumarate (1:1)
- Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, [R-(R*,R*)]-
- Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, [R-(R*,R*)]-, (E)-2-butenedioate (1:1)
- Reconin
- Tavegil
- Tavegyl
- Tavist
- Telgin
- Telgin G
- Trabest
- Xolamin
- See more synonyms
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Found 17 products.
Clemastine Fumarate
CAS:Formula:C21H26ClNO·C4H4O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:459.97CLEMASTINE FUMARATE CRS
CAS:<p>CLEMASTINE FUMARATE CRS</p>Formula:C25H30ClNO5Color and Shape:Crystalline Powder. White. Powder.Molecular weight:459.9624CLEMASTINE FOR SYSTEM SUITABILITY CRS
CAS:<p>CLEMASTINE FOR SYSTEM SUITABILITY CRS</p>Formula:C25H30ClNO5Molecular weight:459.9624Clemastine fumarate
CAS:Clemastine fumarateFormula:C21H26ClNOPurity:74.7%Color and Shape:WhiteMolecular weight:343.17029(2E)-but-2-enedioic acid; (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine
CAS:Formula:C25H30ClNO5Purity:98%Color and Shape:SolidMolecular weight:459.9624Clemastine fumarate
CAS:<p>Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.</p>Formula:C25H30ClNO5Purity:99.52% - >99.99%Color and Shape:Colorless To Faintly Yellow Crystalline Powder Appearance White Or Almost White Crystalline PowderMolecular weight:459.97(R)-2-(2-((R)-1-(4-Chlorophenyl)-1-Phenylethoxy)Ethyl)-1-Methylpyrrolidine Fumarate
CAS:(R)-2-(2-((R)-1-(4-Chlorophenyl)-1-Phenylethoxy)Ethyl)-1-Methylpyrrolidine FumaratePurity:99%Molecular weight:459.96g/molClemastine Fumarate
CAS:Controlled ProductFormula:C21H26ClNO·C4H4O4Color and Shape:NeatMolecular weight:459.96Clemastine Fumarate
CAS:Controlled Product<p>Applications H1 Histamine receptor antagonist. Antihistaminic.<br>References Weidmann, et al.: Boll. Chim. Farm., 106, 467 (1967), Gober, B., et al.: Pharmazie, 43, 539 (1988), Breccia, A., et al.: Curr. Ther. Res., 49, 622 (1991), Schran, H., et al.: J. Clin. Pharmacol., 36, 911 (1996),<br></p>Formula:C21H26ClNO·C4H4O4Color and Shape:WhiteMolecular weight:459.96Clemastine fumarate - Bio-X ™
CAS:<p>Clemastine is an antihistamine drug that has anticholinergic and sedative effects. It is a selective histamine H1 antagonist and binds to the histamine H1 receptor, blocking the action of endogenous histamine. Clemastine is used in cases of allergy or cold. Also, it has shown to reduce the symptoms of the rhinovirus infection, such as, sneezing and rhinorrhea.</p>Formula:C21H26ClNO•C4H4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:459.96 g/molClemastine fumarate
CAS:<p>Histamine (H1) receptor antagonist</p>Formula:C25H30ClNO5Purity:Min. 95%Color and Shape:White PowderMolecular weight:459.96 g/molClemastine-d5 Fumarate
CAS:Controlled ProductFormula:C21D5H21ClNO·C4H4O4Color and Shape:NeatMolecular weight:464.993Clemastine Fumarate
CAS:AntihistaminesFormula:C21H26ClNO·C4H4O4Color and Shape:PowderMolecular weight:343.17029
![(2E)-but-2-enedioic acid; (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrroli…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00HXQN.jpg&w=3840&q=75)
