CAS 149820-74-6

Xemilofiban

Description:

Xemilofiban is a synthetic chemical compound classified as a glycoprotein IIb/IIIa receptor antagonist, primarily used in the context of cardiovascular medicine. It is designed to inhibit platelet aggregation, thereby reducing the risk of thrombus formation in patients with acute coronary syndromes or those undergoing percutaneous coronary interventions. The compound operates by blocking the binding of fibrinogen and other adhesive molecules to the glycoprotein IIb/IIIa receptor on platelets, which is a crucial step in the platelet activation and aggregation process. Xemilofiban is typically administered intravenously and has been studied for its efficacy and safety profile in clinical settings. Its pharmacokinetics involve rapid distribution and elimination, making it suitable for acute treatment scenarios. As with many antiplatelet agents, potential side effects may include bleeding complications, which necessitate careful monitoring during therapy. Overall, Xemilofiban represents a significant advancement in the management of thrombotic cardiovascular events.

Formula: C₁₈H₂₂N₄O₄

InChI: InChI=1S/C18H22N4O4/c1-3-13(11-17(25)26-4-2)21-15(23)9-10-16(24)22-14-7-5-12(6-8-14)18(19)20/h1,5-8,13H,4,9-11H2,2H3,(H3,19,20)(H,21,23)(H,22,24)/t13-/m1/s1

InChI key: InChIKey=ZHCINJQZDFCSEL-CYBMUJFWSA-N

SMILES: [C@H](NC(CCC(NC1=CC=C(C(=N)N)C=C1)=O)=O)(CC(OCC)=O)C#C

Synonyms:

• SC 54684
• Xemilofiban
• 4-Pentynoic acid, 3-[[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino]-, ethyl ester, (S)-
• 4-Pentynoic acid, 3-[[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino]-, ethyl ester, (3S)-

Xemilofiban

CAS: 149820-74-6

Xemilofiban (SC 54684A) interrupts platelet aggregation, promotes thrombosis, and is used in the study of unstable angina.

Formula: C₁₈H₂₂N₄O₄

Purity: 97.05% - 97.36%

Color and Shape: Solid

Molecular weight: 358.39

Ref: TM-T35161

Xemilofiban

CAS: 149820-74-6

Xemilofiban

Purity: ≥95%

Molecular weight: 358.39g/mol

Ref: 54-BUP02381