CAS 149845-06-7
:SAQUINAVIR MESYLATE
Description:
Saquinavir mesylate is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It is a protease inhibitor that works by inhibiting the HIV protease enzyme, which is essential for the viral replication process. The substance appears as a white to off-white crystalline powder and is soluble in organic solvents like methanol and ethanol, but has limited solubility in water. Its molecular formula reflects a complex structure that includes multiple functional groups, contributing to its pharmacological activity. Saquinavir mesylate is typically administered in combination with other antiretroviral agents to enhance its efficacy and reduce the likelihood of resistance development. The compound is known for its relatively short half-life, necessitating multiple daily doses to maintain therapeutic levels in the bloodstream. Additionally, it may have side effects, including gastrointestinal disturbances and potential interactions with other medications, which necessitate careful monitoring during treatment. Overall, saquinavir mesylate plays a significant role in the management of HIV infection, contributing to improved patient outcomes when used appropriately.
Formula:C38H50N6O5·CH4O3S
InChI:InChI=1S/C38H50N6O5.CH4O3S/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29;1-5(2,3)4/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49);1H3,(H,2,3,4)/t26-,27+,30-,31-,32-,33+;/m0./s1
InChI key:InChIKey=IRHXGOXEBNJUSN-YOXDLBRISA-N
SMILES:C([C@H]([C@H](CC1=CC=CC=C1)NC([C@@H](NC(=O)C2=NC3=C(C=C2)C=CC=C3)CC(N)=O)=O)O)N4[C@H](C(NC(C)(C)C)=O)C[C@]5([C@@](C4)(CCCC5)[H])[H].S(C)(=O)(=O)O
Synonyms:- (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide Mesylate
- Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, monomethanesulfonate (salt) (9CI)
- Butanediamide, N1-[3-[3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, [3S-[2[1R*(R*),2S*],3a,4ab,8ab]]-, monomethanesulfonate (salt)
- Butanediamide, N<sup>1</sup>-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, methanesulfonate (1:1)
- Butanediamide, N<sup>1</sup>-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, monomethanesulfonate (salt)
- Butanediamide, N<sup>1</sup>-[3-[3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, [3S-[2[1R*(R*),2S*],3α,4aβ,8aβ]]-, monomethanesulfonate (salt)
- Fortovase
- Invirase
- N~1~-{(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl]-3-hydroxy-1-phenylbutan-2-yl}-N~2~-(quinolin-2-ylcarbonyl)-L-aspartamide methanesulfonate (1:1)
- Ro 31-895
- Ro 31-8959
- Ro 31-8959/003
- Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, monomethanesulfonate (salt)
- Saquinavir mesylate
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Found 14 products.
SAQUINAVIR MESILATE CRS
CAS:<p>SAQUINAVIR MESILATE CRS</p>Formula:C39H54N6O8SColor and Shape:White. Powder., White. Powder.Molecular weight:766.9465SAQUINAVIR FOR SYSTEM SUITABILITY CRS
CAS:<p>SAQUINAVIR FOR SYSTEM SUITABILITY CRS</p>Formula:C39H54N6O8SMolecular weight:766.9465Saquinavir Mesylate
CAS:Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fusedFormula:C38H50N6O5·CH4O3SColor and Shape:White Off-White Fine PowderMolecular weight:670.38427Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, methanesulfonate (1:1)
CAS:Formula:C39H54N6O8SPurity:99%Color and Shape:SolidMolecular weight:766.9465Saquinavir Mesylate
CAS:Formula:C38H50N6O5·CH4O3SColor and Shape:White To Off-White SolidMolecular weight:670.86 96.11Saquinavir mesylate
CAS:Formula:C38H50N6O5·CH4O3SPurity:≥ 98%Color and Shape:White powder or solidMolecular weight:766.95Saquinavir mesylate
CAS:<p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>Formula:C39H54N6O8SPurity:99.19%Color and Shape:White Or Pale Yellow PowderMolecular weight:766.9Saquinavir Mesylate
CAS:Controlled Product<p>Applications A selective HIV protease inhibitor. Antiviral.<br>References Roberts, N.A., et al.: Science, 248, 358 (1990), Craig, J.C., et al.: Antiviral Res., 16, 295 (1991),<br></p>Formula:C38H50N6O5·CH4O3SColor and Shape:NeatMolecular weight:766.95Saquinavir mesylate - Bio-X ™
CAS:<p>Saquinavir is a HIV protease inhibitor drug that is used with other antiretroviral drugs for the treatment of HIV-1. As this drug prevents HIV protease activity, it prevents the proteolysis of the Gag polyprotein and thus results in non-infectious virus particles.</p>Formula:C38H50N6O5•CH4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:766.95 g/molSaquinavir mesylate
CAS:<p>Anti-viral; HIV protease inhibitor</p>Formula:C38H50N6O5•CH4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:766.95 g/mol
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