CAS 14985-44-5

8-BROMO-2'-DEOXYADENOSINE

Description:

8-Bromo-2'-deoxyadenosine is a modified nucleoside that serves as an important tool in biochemical research, particularly in studies involving DNA and RNA. Its structure consists of a deoxyribose sugar linked to an adenine base, with a bromine atom substituted at the 8-position of the purine ring. This substitution can influence the nucleoside's properties, such as its ability to participate in hydrogen bonding and its overall stability. The compound is often used in studies of nucleic acid interactions, as well as in the development of antiviral and anticancer agents due to its potential to interfere with normal nucleic acid metabolism. Additionally, 8-bromo-2'-deoxyadenosine can act as a substrate for various enzymes, allowing researchers to investigate enzyme kinetics and mechanisms. Its unique characteristics make it a valuable compound in molecular biology and medicinal chemistry. However, handling this substance requires caution due to its reactivity and potential biological effects.

Formula: C₁₀H₁₂BrN₅O₃

InChI: InChI=1/C10H12BrN5O3/c11-10-15-7-8(12)13-3-14-9(7)16(10)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,13,14)

SMILES: C1C(C(CO)OC1n1c2c(c(N)ncn2)nc1Br)O

Synonyms:

• 8-Bromo-2'-Deoxyadenosine, Hplc Purified, 98% Pure With Hplc Uv Chromatogram
• 8-Bromo-2'-Deoxy-D-Adenosine
• 8-bromo-9-(2-deoxypentofuranosyl)-9H-purin-6-amine

8-Bromo-2'-deoxyadenosine, 99%

CAS: 14985-44-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₂BrN₅O₃

Purity: 99%

Molecular weight: 330.14

Ref: 02-J65357

Adenosine, 8-bromo-2'-deoxy-

CAS: 14985-44-5

Formula: C₁₀H₁₂BrN₅O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 330.1380

Ref: IN-DA001M2V

5-(6-amino-8-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

CAS: 14985-44-5

5-(6-amino-8-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

Purity: ≥95%

Ref: 54-OR22721

8-Bromo-2''-deoxyadenosine

CAS: 14985-44-5

Formula: C₁₀H₁₃FN₆O₃

Purity: ≥ 97.0%

Color and Shape: White to yellow or tan powder

Molecular weight: 284.25

Ref: 7W-GE1449

8-Bromo-2'-deoxyadenosine

CAS: 14985-44-5

8-Bromo-2'-deoxyadenosine is a 2'-Deoxynucleoside; Halo-nucleoside.

Formula: C₁₀H₁₂BrN₅O₃

Color and Shape: Solid

Molecular weight: 330.14

Ref: TM-TNU0793

8-Bromo-2'-deoxyadenosine

CAS: 14985-44-5

8-Bromo-2'-deoxyadenosine (8-BrdA) is a reactive chemical that can be used in the study of DNA. It is used to measure the kinetics of oxidative dna damage and to study glycosidic bond cleavage reactions. 8-BrdA reacts with eosinophil peroxidase to yield an oxidant, which can then react with dna duplexes. This reaction has been shown to affect both intramolecular and intermolecular hydrogen bonds. 8-BrdA also has been shown to induce cell death in vitro by apoptosis.

Formula: C₁₀H₁₂BrN₅O₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 330.14 g/mol

Ref: 3D-NB05283

8-BROMO-2′-DEOXYADENOSINE

CAS: 14985-44-5

Formula: C₁₀H₁₂BrN₅O₃

Purity: 96%

Molecular weight: 330.142

Ref: 10-F334241

8-Bromo-2’-deoxyadenosine-13C2,15N

Controlled Product

CAS: 14985-44-5

Formula: C₂C₈H₁₂Br₁₅NN₄O₃

Color and Shape: Neat

Molecular weight: 333.117

Ref: TR-B682862