CAS 1499-59-8

Pregnane-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-, (5β)-

Description:

Pregnane-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-, (5β)-, commonly known as a synthetic steroid, is characterized by its complex structure that includes multiple functional groups, specifically ketones and hydroxyl groups. This compound is derived from the pregnane steroid backbone, which consists of a steroid nucleus with a total of 21 carbon atoms. The presence of the acetyloxy group indicates that it has an ester functional group, which can influence its solubility and biological activity. The hydroxyl group at the 17 position contributes to its potential as a hormone or hormone analog, affecting its interaction with steroid receptors. The specific stereochemistry, denoted by the (5β) configuration, plays a crucial role in determining the compound's pharmacological properties and its mechanism of action in biological systems. Overall, this compound is of interest in medicinal chemistry and pharmacology, particularly in the context of steroid hormone research and therapeutic applications.

Formula: C₂₃H₃₂O₆

InChI: InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h14,16-17,20,28H,4-12H2,1-3H3/t14-,16+,17+,20-,21+,22+,23+/m1/s1

InChI key: InChIKey=AZCNJEFLSOQGST-LPEMZKRWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@](C(=O)C1)([C@]4(C)[C@](CC3)(CC(=O)CC4)[H])[H])[H])(CC[C@@]2(C(COC(C)=O)=O)O)[H]

Synonyms:

• (5Beta)-17-Hydroxy-3,11,20-Trioxopregnan-21-Yl Acetate
• (5Beta,17Xi)-17-Hydroxy-3,11,20-Trioxopregnan-21-Yl Acetate
• 17,21-Dihydroxy-5β-pregnane-3,11,20-trione 21-acetate
• 17-Hydroxy-3,11,20-Trioxopregnan-21-Yl Acetate
• 17-alpha,21-Dihydroxy-5-beta-pregnane-3,11,20-trione 21-acetate
• 17α,21-Dihydroxy-5β-pregnane-3,11,20-trione 21-acetate
• 5β-Pregnane-3,11,20-trione, 17,21-dihydroxy-, 21-acetate
• Dihydrocortisone acetate
• L 491297-0
• Nsc 22843
• Pregnane-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-, (5beta)- (9CI)

5b-Dihydrocortisone Acetate 21-Acetate

CAS: 1499-59-8

Formula: C₂₃H₃₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 404.4966

Ref: IN-DA001M3Y

5β-Dihydrocortisone Acetate 21-Acetate

Controlled Product

CAS: 1499-59-8

Applications Cortisone (C696500) derivative.

Formula: C₂₃H₃₂O₆

Color and Shape: Neat

Molecular weight: 404.5

Ref: TR-D448840

Dihydrocortisone 21-acetate

Controlled Product

CAS: 1499-59-8

Dihydrocortisone 21-acetate is a synthetic steroid hormone that has radical mechanism of action. It is used to treat inflammatory and autoimmune diseases, such as rheumatoid arthritis, lupus erythematosus, dermatitis herpetiformis, myasthenia gravis, and Behçet's disease. This drug can be synthesized from the reaction of prednisolone with acetyl chloride. Dihydrocortisone 21-acetate is an ester of hydrocortisone or cortisone. It may also be obtained from plant sources by hydrolysis of chlorocarbonates. Dihydrocortisone 21-acetate is freely soluble in dimethylformamide (DMF) and tetrazolium salts are used as the indicator for its presence.

Formula: C₂₃H₃₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 404.5 g/mol

Ref: 3D-FD66539