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CAS 149908-53-2

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Azimilide

Description:
Azimilide is a chemical compound that belongs to the class of antiarrhythmic agents, specifically designed to treat cardiac arrhythmias. It functions primarily as a potassium channel blocker, which helps to stabilize the cardiac membrane and restore normal rhythm by prolonging the action potential duration. Azimilide exhibits a unique pharmacological profile, offering both antiarrhythmic properties and a relatively favorable side effect profile compared to other agents in its class. The compound has been studied for its efficacy in managing atrial fibrillation and ventricular tachycardia. Its chemical structure includes specific functional groups that contribute to its biological activity and solubility characteristics. Azimilide's mechanism of action involves selective inhibition of certain ion channels, which is crucial for its therapeutic effects. While it has shown promise in clinical settings, its use may be limited by potential drug interactions and the need for careful monitoring of cardiac function. Overall, Azimilide represents an important development in the field of cardiology, particularly for patients with complex arrhythmic conditions.
Formula:C23H28ClN5O3
InChI:InChI=1S/C23H28ClN5O3/c1-26-12-14-27(15-13-26)10-2-3-11-28-22(30)17-29(23(28)31)25-16-20-8-9-21(32-20)18-4-6-19(24)7-5-18/h4-9,16H,2-3,10-15,17H2,1H3
InChI key:InChIKey=MREBEPTUUMTTIA-UHFFFAOYSA-N
SMILES:C(=NN1C(=O)N(CCCCN2CCN(C)CC2)C(=O)C1)C=3OC(=CC3)C4=CC=C(Cl)C=C4
Synonyms:
  • 1-[[[5-(4-Chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione
  • 2,4-Imidazolidinedione, 1-(((5-(4-chlorophenyl)-2-furanyl)methylene)amino)-3-(4-(4-methyl-1-piperazinyl)butyl)-
  • Azimilide [INN:BAN]
  • Unii-74Qu6P2934
  • Azimilide
  • Azimilide
  • (NE-10064)
  • AZIMILIDE USP/EP/BP
  • NE-10064
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Found 3 products.