CAS 149934-21-4: 9-Amino Minocycline Hydrochloride

Description: 9-Amino Minocycline Hydrochloride is a derivative of minocycline, a broad-spectrum antibiotic belonging to the tetracycline class. This compound is characterized by the presence of an amino group at the 9-position of the minocycline structure, which enhances its antibacterial activity and pharmacological properties. It is typically presented as a hydrochloride salt, which improves its solubility in aqueous solutions, making it suitable for various pharmaceutical formulations. The substance exhibits a wide range of antibacterial activity against both Gram-positive and Gram-negative bacteria, and it is often used in the treatment of infections, including those caused by resistant strains. Additionally, 9-Amino Minocycline Hydrochloride has anti-inflammatory properties, which can be beneficial in treating conditions like acne and other dermatological disorders. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 30S ribosomal subunit. As with other tetracyclines, it is important to consider potential side effects and contraindications, including photosensitivity and interactions with certain metal ions.

Formula: C₂₃H₃₀N₄O₁₁S

InChI: InChI=1S/C23H28N4O7.ClH/c1-26(2)12-7-11(24)17(28)14-9(12)5-8-6-10-16(27(3)4)19(30)15(22(25)33)21(32)23(10,34)20(31)13(8)18(14)29;/h7-8,10,16,28,30-31,34H,5-6,24H2,1-4H3,(H2,25,33);1H/t8-,10-,16-,23-;/m0./s1

InChI key: InChIKey=KYFXMIINWSZGCG-KBTHSJHISA-N

SMILES: Cl.O=C(N)C=1C(=O)C2(O)C(O)=C3C(=O)C=4C(O)=C(N)C=C(C4CC3CC2C(C1O)N(C)C)N(C)C

Synonyms:

• (4S,4As,5Ar,12As)-9-Amino-4,7-Bis(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,10,12,12A-Tetrahydroxy-1,11-Dioxo-2-Naphthacenecarboxamide Hydrochloride
• (4S,4As,5Ar,12As)-9-Amino-4,7-Bis(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,10,12,12A-Tetrahydroxy-1,11-Dioxo-2-Naphthacenecarboxamide Hydrochloride (1:1)
• (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide sulfate (1:1)
• 2-Naphthacenecarboxamide, 9-amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aR,12aS)-
• 2-Naphthacenecarboxamide, 9-amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,12aα)]-
• 9-Aminominocycline hydrochloride

Tigecycline impurity B CRS

CAS: 149934-21-4

Tigecycline Related Compound B ((4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- carboxamide hydrochloride (1:x))

CAS: 149934-21-4

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

• Formula: C₂₃H₂₈N₄O₇·HCl
• Color and Shape: Off-White Powder
• Molecular weight: 472.1958

2-Naphthacenecarboxamide, 9-amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aR,12aS)-

CAS: 149934-21-4

• Formula: C₂₃H₂₉ClN₄O₇
• Purity: 96%
• Color and Shape: Solid
• Molecular weight: 508.952

Tigecycline EP Impurity B HCl (Tigecycline Metabolite M6 HCl, 9-Amino Minocycline HCl)

CAS: 149934-21-4

• Formula: C₂₃H₂₈N₄O₇·HCl
• Color and Shape: Yellow Solid
• Molecular weight: 472.50 36.46

9-Amino minocycline hydrochloride

CAS: 149934-21-4

• Purity: 96% HPLC
• Molecular weight: 508.959991455078

9-Aminominocycline Hydrochloride (~90%)

CAS: 149934-21-4

Applications 9-Aminominocycline Hydrochloride is a metabolite of Minocycline Hydrochloride (M344800); a second generation tetracycline antibiotic …

• Formula: C₂₃H₂₈N₄O₇•HCl
• Purity: ~90%
• Color and Shape: Neat
• Molecular weight: 508.95

9-Aminominocycline hydrochloride

CAS: 149934-21-4

Aminominocycline hydrochloride is a synthetic, catalytic compound. It is used as a reaction solution in …

• Formula: C₂₃H₂₈N₄O₇·HCl
• Purity: Min. 80 Area-%
• Color and Shape: Yellow Powder
• Molecular weight: 508.95 g/mol