CAS 149950-60-7

Emivirine

Description:

Emivirine, with the CAS number 149950-60-7, is a synthetic compound that belongs to the class of non-nucleoside reverse transcriptase inhibitors (NNRTIs). It is primarily investigated for its potential use in the treatment of HIV/AIDS. Emivirine functions by binding to the reverse transcriptase enzyme, which is crucial for the replication of the HIV virus, thereby inhibiting its activity and preventing viral replication. The compound exhibits a unique chemical structure that differentiates it from other NNRTIs, contributing to its efficacy and resistance profile. Emivirine has been studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, which are essential for determining its therapeutic potential and safety profile. While it has shown promise in clinical trials, its use in practice may depend on factors such as resistance patterns and patient-specific considerations. As with any pharmaceutical agent, understanding its mechanism of action, side effects, and interactions with other medications is crucial for effective treatment planning.

Formula: C₁₇H₂₂N₂O₃

InChI: InChI=1S/C17H22N2O3/c1-4-22-11-19-14(10-13-8-6-5-7-9-13)15(12(2)3)16(20)18-17(19)21/h5-9,12H,4,10-11H2,1-3H3,(H,18,20,21)

InChI key: InChIKey=MLILORUFDVLTSP-UHFFFAOYSA-N

SMILES: C(C1=C(C(C)C)C(=O)NC(=O)N1COCC)C2=CC=CC=C2

Synonyms:

• MKC 442
• Emivirine
• I-EBU
• 2,4(1H,3H)-Pyrimidinedione, 1-(ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)-
• 1-(Ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)-2,4(1H,3H)-pyrimidinedione

6-Benzyl-1-(ethoxymethyl)-5-isopropylpyrimidine-2,4(1H,3H)-dione

CAS: 149950-60-7

Formula: C₁₇H₂₂N₂O₃

Purity: 98%

Molecular weight: 302.3682

Ref: IN-DA001M5U

Emivirine

CAS: 149950-60-7

Emivirine

Purity: ≥98%

Molecular weight: 302.37g/mol

Ref: 54-BUP11462

Emivirine Isopropyl-d6

Controlled Product

CAS: 149950-60-7

Formula: C₁₇D₆H₁₆N₂O₃

Color and Shape: Neat

Molecular weight: 308.405

Ref: TR-E146592

Emivirine

Controlled Product

CAS: 149950-60-7

Formula: C₁₇H₂₂N₂O₃

Color and Shape: Neat

Molecular weight: 302.368

Ref: TR-E146590

Emivirine

CAS: 149950-60-7

Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.

Formula: C₁₇H₂₂N₂O₃

Purity: 99.8%

Color and Shape: Solid

Molecular weight: 302.37

Ref: TM-T27260