CAS 14997-58-1

N-[(Phenylmethoxy)carbonyl]-L-histidine

Description:

N-[(Phenylmethoxy)carbonyl]-L-histidine, with the CAS number 14997-58-1, is a derivative of the amino acid histidine, which is known for its role in protein synthesis and various metabolic processes. This compound features a phenylmethoxycarbonyl group attached to the nitrogen of the histidine side chain, which enhances its stability and solubility compared to unmodified histidine. The presence of the phenylmethoxy group contributes to its hydrophobic characteristics, potentially influencing its interactions in biological systems. This compound may exhibit specific biological activities, making it of interest in pharmaceutical and biochemical research. Its structure allows for potential applications in drug design, particularly in the development of peptide-based therapeutics. Additionally, the compound's properties, such as solubility, stability, and reactivity, can be influenced by factors like pH and temperature, which are critical for its application in various chemical and biological contexts. Overall, N-[(Phenylmethoxy)carbonyl]-L-histidine represents a valuable compound in the study of amino acid derivatives and their functional roles in biochemistry.

Formula: C₁₄H₁₅N₃O₄

InChI: InChI=1/C14H15N3O4/c18-13(19)12(6-11-7-15-9-16-11)17-14(20)21-8-10-4-2-1-3-5-10/h1-5,7,9,12H,6,8H2,(H,15,16)(H,17,20)(H,18,19)/t12-/m0/s1

InChI key: InChIKey=WCOJOHPAKJFUDF-LBPRGKRZSA-N

SMILES: [C@@H](CC1=CN=CN1)(NC(OCC2=CC=CC=C2)=O)C(O)=O

Synonyms:

• (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(1H-imidazol-4-yl)propanoic acid
• (Benzyloxycarbonyl)histidine
• <span class="text-smallcaps">L</span>-Histidine, N-[(phenylmethoxy)carbonyl]-
• CBZ-L-Histidine-OH
• Cbz-L-histidine
• Histidine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• N(alpha)-Benzyloxycarbonyl-L-histidine~Z-His-OH
• N(alpha)-Cbz-L-histidine
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-histidine
• N-(Benzyloxycarbonyl)-S-histidine
• N-(alpha)-Carbobenzoxy-L-histidine
• N-Benzyloxycarbonyl-L-histidine
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-histidine
• N-Carbobenzoxyhistidine
• N-Cbz-L-histidine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-histidine
• N-[(benzyloxy)carbonyl]histidine
• N-alpha-carbobenzyloxy-L-histidine
• N-α-Carbobenzyloxy-<span class="text-smallcaps">L</span>-histidine
• N^α-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-histidine
• N^α-(Benzyloxycarbonyl)histidine
• NALPHA-Benzyloxycarbonyl-L-histidine
• Z-His
• Z-His-OH
• N-[(Phenylmethoxy)carbonyl]-L-histidine
• Histidine, N-carboxy-, N-benzyl ester, L-
• N-Carbobenzoxy-L-histidine
• L-Histidine, N-[(phenylmethoxy)carbonyl]-
• N-ALPHA-Z-L-HISTIDINE
• N-ALPHA-BENZYLOXYCARBONYL-L-HISTIDINE
• Z-L-HISTIDINE
• (S)-2-BENZYLOXYCARBONYLAMINO-3-(3H-IMIDAZOL-4-YL)-PROPIONIC ACID
• CBZ-L-HIS-OH
• N2-CARBOBENZYLOXY-L-HISTIDINE
• N
• NALPHA-CARBOBENZOXY-L-HISTIDINE
• CBZ-HIS-OH
• α
• -Carbobenzyloxy-L-histidine
• -Z-L-Histidine
• Z-HISTIDINE

Nα-Carbobenzoxy-L-histidine

CAS: 14997-58-1

Formula: C₁₄H₁₅N₃O₄

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 289.29

Ref: 3B-B0265

N(α)-Benzyloxycarbonyl-L-histidine, 98+%

CAS: 14997-58-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₄H₁₅N₃O₄

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 289.29

Ref: 02-L09114

Z-His-OH

CAS: 14997-58-1

Formula: C₁₄H₁₅N₃O₄

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 289.29

Ref: 01-4000625

L-Histidine, N-[(phenylmethoxy)carbonyl]-

CAS: 14997-58-1

Formula: C₁₄H₁₅N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 289.2866

Ref: IN-DA00HXR6

N-Cbz-L-histidine

CAS: 14997-58-1

N-Cbz-L-histidine

Purity: 98%

Molecular weight: 289.29g/mol

Ref: 54-OR1014326

Z-His-OH

CAS: 14997-58-1

Formula: C₁₄H₁₅N₃O₄

Molecular weight: 289.29

Ref: 7W-GM7205

Z-His-OH

CAS: 14997-58-1

M03075 - Z-His-OH

Formula: C₁₄H₁₅N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 289.291

Ref: 10-M03075

N-alpha-Z-L-histidine

CAS: 14997-58-1

N-alpha-Z-L-histidine is a nitrogenous compound that is an amide formed by the reaction of histidine and trifluoroacetic acid. It has been shown to be anticancer and to have an effect on tumor vasculature, with efficacy against solid tumors. N-alpha-Z-L-histidine inhibits the cell cycle at the G1 phase and blocks DNA synthesis, which arrests cells in the M phase. This drug also inhibits tumor angiogenesis by blocking vascular endothelial growth factor (VEGF) signaling. N-alpha-Z-L-histidine is a molecule that has been synthesized using solid phase chemistry and purified by high performance liquid chromatography.

Formula: C₁₄H₁₅N₃O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 289.29 g/mol

Ref: 3D-FH47279

Z-L-Histidine extrapure, 99%

CAS: 14997-58-1

Formula: C₁₄H₁₅N₃O₄

Purity: min. 99%

Color and Shape: White to off white, Crystalline powder

Molecular weight: 289.30

Ref: SR-57156