CAS 149979-74-8

Terbogrel

Description:

Terbogrel, with the CAS number 149979-74-8, is a chemical compound that functions primarily as an antiplatelet agent. It is designed to inhibit platelet aggregation, thereby reducing the risk of thrombus formation in cardiovascular conditions. Terbogrel acts by selectively blocking the P2Y12 receptor, which plays a crucial role in the activation of platelets in response to adenosine diphosphate (ADP). This mechanism of action is similar to that of other antiplatelet drugs, but Terbogrel is noted for its potential to provide a more favorable safety profile and reduced risk of bleeding complications. The compound is typically administered orally and has been investigated for its efficacy in various clinical settings, particularly in patients with a history of cardiovascular events. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are essential for understanding its therapeutic potential and optimizing dosing regimens. As with any medication, the use of Terbogrel should be guided by clinical considerations and patient-specific factors.

Formula: C₂₃H₂₇N₅O₂

InChI: InChI=1S/C23H27N5O2/c1-23(2,3)28-22(26-16-24)27-19-10-6-8-17(14-19)20(11-4-5-12-21(29)30)18-9-7-13-25-15-18/h6-11,13-15H,4-5,12H2,1-3H3,(H,29,30)(H2,26,27,28)/b20-11+

InChI key: InChIKey=XUTLOCQNGLJNSA-RGVLZGJSSA-N

SMILES: C(=C\CCCC(O)=O)(\C1=CC(N=C(NC(C)(C)C)NC#N)=CC=C1)/C=2C=CC=NC2

Synonyms:

• Terbogrel
• (5E)-6-[3-[[(Cyanoamino)[(1,1-dimethylethyl)amino]methylene]amino]phenyl]-6-(3-pyridinyl)-5-hexenoic acid
• 5-Hexenoic acid, 6-[3-[[(cyanoamino)[(1,1-dimethylethyl)amino]methylene]amino]phenyl]-6-(3-pyridinyl)-, (E)-
• 5-Hexenoic acid, 6-[3-[[(cyanoamino)[(1,1-dimethylethyl)amino]methylene]amino]phenyl]-6-(3-pyridinyl)-, (5E)-
• (5E)-6-[m-(3-tert-Butyl-2-cyanoguanidino)phenyl]-6-(3-pyridyl)-5-hexenoic acid

Terbogrel

CAS: 149979-74-8

Terbogrel

Purity: ≥98%

Molecular weight: 405.49g/mol

Ref: 54-BUP12819

Terbogrel

CAS: 149979-74-8

Terbogrel is a pharmaceutical compound that functions as both a thromboxane synthase inhibitor and a thromboxane receptor antagonist, which is synthesized via chemical processes in a laboratory setting. Its mode of action involves the dual inhibition of thromboxane A2 synthesis and blockade of thromboxane A2 receptors, leading to a reduction in platelet aggregation and vasoconstriction. This dual mechanism effectively disrupts the pro-thrombotic and vasoconstrictive pathways mediated by thromboxane A2.

Formula: C₂₃H₂₇N₅O₂

Purity: Min. 95%

Molecular weight: 405.5 g/mol

Ref: 3D-ZFA97974

Terbogrel

CAS: 149979-74-8

Terbogrel is an antiplatelet drug, blocking thromboxane A2 receptor/synthase. Helps prevent clots.

Formula: C₂₃H₂₇N₅O₂

Purity: 98.95%

Color and Shape: Solid

Molecular weight: 405.49

Ref: TM-T17039