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CAS 149989-64-0

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DMT-2'O-TBDMS-RA(TAC) AMIDITE 0.5G AB

Description:
DMT-2'O-TBDMS-RA(TAC) amidite is a specialized chemical compound primarily used in the field of nucleic acid synthesis, particularly for the solid-phase synthesis of oligonucleotides. The compound features a dimethoxytrityl (DMT) protecting group, which is crucial for the selective protection of the 5' hydroxyl group of nucleotides during synthesis. The presence of the TBDMS (tert-butyldimethylsilyl) group provides additional protection for the 2' hydroxyl group, enhancing the stability and reactivity of the nucleotide during the synthesis process. The "RA(TAC)" designation indicates that this amidite is designed for specific applications, likely involving the incorporation of modified nucleotides or facilitating the synthesis of RNA sequences. As a solid, it is typically handled under inert conditions to prevent moisture absorption, which can affect its reactivity. Overall, this compound is essential for researchers working on oligonucleotide synthesis, enabling the production of complex RNA and DNA sequences with high fidelity and efficiency.
Formula:C58H76N7O9PSi
Synonyms:
  • Dmt-2'O-Tbdms-Ra(Tac) Amidite 0.5G 89
  • DMT-2'O-TBDMS-rA(tac) Amidite 5g, Singl.
  • DMT-2'O-TBDMS-rA(tac) Amidite 10g, Singl
  • DMT-2'O-TBDMS-rA(tac) Amidite 10g,6Pack
  • DMT-2'O-TBDMS-rC(tac) Amidite
  • DMT-2'O-TBDMS-rA(tac) Amidite 2,5g, 12Pa
  • DMT-2'O-TBDMS-rA(tac) Amidite 4g, 12Pack
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Found 1 products.
  • 2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite
    Biosynth
    + Info

    2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite

    CAS:
    <p>2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleoside. This is an anticancer drug that inhibits the growth of cancer cells by inhibiting DNA synthesis and RNA synthesis. It is a novel compound that has been shown to be an activator of cellular proliferation in vitro. 2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite is used as a monophosphate nucleoside synthase inhibitor in the treatment of cancer.</p>
    Formula:C58H76N7O9PSi
    Purity:Min. 95%
    Molecular weight:1,074.33 g/mol

    Ref: 3D-PB63472

    1g
    327.00€
    2g
    486.00€
    5g
    1,007.00€
    10g
    1,518.00€
    500mg
    211.00€