CAS 150045-04-8
:histogranin
Description:
Histogranin, identified by the CAS number 150045-04-8, is a peptide that is primarily associated with the regulation of various physiological processes, particularly in the context of the immune system and inflammation. It is derived from the granins family of proteins, which are known for their role in the storage and release of hormones and neuropeptides. Histogranin exhibits characteristics typical of peptides, including a specific sequence of amino acids that determines its biological activity and interactions with receptors. This substance is often studied for its potential implications in neurobiology and its role in modulating immune responses. Additionally, histogranin may have applications in research related to cancer and other diseases, as its expression levels can vary in different pathological conditions. Its stability, solubility, and reactivity are influenced by environmental factors such as pH and temperature, which are critical for its function in biological systems. Overall, histogranin represents a significant area of interest in biochemical and medical research.
Formula:C78H119N21O21S
InChI:InChI=1/C78H119N21O21S/c1-41(2)32-54(94-66(108)43(5)89-72(114)57(35-47-20-24-49(102)25-21-47)97-75(117)58(37-61(82)104)95-67(109)50(80)28-31-121-7)73(115)93-51(16-11-12-29-79)68(110)86-39-63(106)91-53(26-27-60(81)103)69(111)87-38-62(105)90-52(17-13-30-85-78(83)84)71(113)99-65(44(6)100)76(118)98-55(33-42(3)4)74(116)96-56(34-46-18-22-48(101)23-19-46)70(112)88-40-64(107)92-59(77(119)120)36-45-14-9-8-10-15-45/h8-10,14-15,18-25,41-44,50-59,65,100-102H,11-13,16-17,26-40,79-80H2,1-7H3,(H2,81,103)(H2,82,104)(H,86,110)(H,87,111)(H,88,112)(H,89,114)(H,90,105)(H,91,106)(H,92,107)(H,93,115)(H,94,108)(H,95,109)(H,96,116)(H,97,117)(H,98,118)(H,99,113)(H,119,120)(H4,83,84,85)/t43-,44+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,65-/m0/s1
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Found 1 products.
Histogranin
CAS:<p>Histogranin H is a glycoprotein that is secreted by gland cells. Histogranin H has been shown to have pharmacological effects on locomotor activity and pain in animal models. This protein has also been shown to inhibit cancer growth in vitro and in vivo. In addition, it has a protective effect on the central nervous system, which may be due to its ability to increase the expression of brain-derived neurotrophic factor (BDNF). It also inhibits the proliferation of glioma cells, which are cancerous tumors that originate from glial cells in the brain. Histogranin H binds to histone proteins and glutamate receptors, which leads to an antinociceptive effect when injected into rats. The antinociceptive effect of this protein is attenuated by trypsin treatment. Histogranin H has also been shown to have an analgesic effect when injected into rats with chronic pain models.</p>Formula:C78H119N21O21SPurity:Min. 95%Molecular weight:1,718.97 g/mol
