CAS 15005-62-6

β-Alanine, N-[(2S)-2-[[glycyl-(3R)-3-methyl-L-prolyl-L-valyl]amino]-1-imino-3,3-dimethylbutyl]-3-methyl-L-valyl-(βS)-β-methyl-L-phenylalanyl-3-(2-thiazolyl)-, methyl ester, cyclic (1→1′)-imine, (3R)-

Description:

The chemical substance known as β-Alanine, N-[(2S)-2-[[glycyl-(3R)-3-methyl-L-prolyl-L-valyl]amino]-1-imino-3,3-dimethylbutyl]-3-methyl-L-valyl-(βS)-β-methyl-L-phenylalanyl-3-(2-thiazolyl)-, methyl ester, cyclic (1→1′)-imine, (3R)-, with CAS number 15005-62-6, is a complex peptide derivative. It features a β-alanine backbone and incorporates multiple amino acid residues, including glycine, proline, valine, and phenylalanine, which contribute to its structural diversity and potential biological activity. The presence of a thiazole ring suggests possible interactions with biological systems, potentially influencing its pharmacological properties. This compound may exhibit characteristics typical of peptides, such as solubility in polar solvents and the ability to form hydrogen bonds due to its amino and carboxyl functional groups. Its cyclic imine structure may also impart stability and influence its reactivity. Overall, this substance could be of interest in biochemical research, particularly in studies related to peptide synthesis, drug design, and the exploration of its biological functions.

Formula: C₄₂H₆₂N₈O₇S

InChI: InChI=1S/C42H62N8O7S/c1-23(2)30-36(53)49-33(41(5,6)7)35(44-22-28(51)50-19-17-24(3)32(50)38(55)46-30)48-34(42(8,9)10)39(56)47-31(25(4)26-15-13-12-14-16-26)37(54)45-27(21-29(52)57-11)40-43-18-20-58-40/h12-16,18,20,23-25,27,30-34H,17,19,21-22H2,1-11H3,(H,44,48)(H,45,54)(H,46,55)(H,47,56)(H,49,53)/t24-,25+,27-,30+,31+,32+,33-,34-/m1/s1

InChI key: InChIKey=KSIZLOPUXFSFNR-XZNJZDOZSA-N

SMILES: O=C1[C@]2(N(C(=O)CN=C(N[C@H](C(N[C@@H]([C@@H](C)C3=CC=CC=C3)C(N[C@H](CC(OC)=O)C4=NC=CS4)=O)=O)C(C)(C)C)[C@H]([C@@](C)(C)C)NC(=O)[C@H]([C@H](C)C)N1)CC[C@H]2C)[H]

Synonyms:

• Pyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine, cyclic peptide deriv.
• I 337B
• Bottromycic A2 acid, methyl ester
• Bottromycin A2
• β-Alanine, N-[(2S)-2-[[glycyl-(3R)-3-methyl-L-prolyl-L-valyl]amino]-1-imino-3,3-dimethylbutyl]-3-methyl-L-valyl-(βS)-β-methyl-L-phenylalanyl-3-(2-thiazolyl)-, methyl ester, cyclic (1→1′)-imine, (3R)-

Bottromycin A2

CAS: 15005-62-6

Bottromycin A2, an antibiotic from Streptomyces, halts protein synthesis and targets MRSA, VRE (MIC: 1, 0.5 μg/ml).

Formula: C₄₂H₆₂N₈O₇S

Color and Shape: Solid

Molecular weight: 823.07

Ref: TM-T36706

Bottromycin A2

CAS: 15005-62-6

Bottromycin A2 is a peptide antibiotic, which is a natural product derived from the fermentation of certain Streptomyces strains. It operates by targeting the bacterial ribosome, specifically inhibiting protein synthesis. The mode of action involves binding to the A-site of the 50S ribosomal subunit, thereby preventing the correct positioning of transfer RNA (tRNA) during translation. This inhibition halts the growth of bacteria by disrupting essential protein production processes.

Formula: C₄₂H₆₂N₈O₇S

Purity: Min. 95%

Molecular weight: 823.1 g/mol

Ref: 3D-QAA00562