ABCB1-IN-4, with the CAS number 1500779-21-4, is a chemical compound that serves as an inhibitor of the ABCB1 protein, also known as P-glycoprotein. This protein plays a crucial role in the transport of various substances across cellular membranes, influencing drug absorption, distribution, and excretion. ABCB1-IN-4 is primarily studied for its potential applications in enhancing the efficacy of certain chemotherapeutic agents by inhibiting the efflux activity of P-glycoprotein, thereby increasing drug accumulation in cancer cells. The compound is characterized by its specific molecular structure, which allows it to interact with the binding site of the ABCB1 protein. Its pharmacological properties, including solubility, stability, and bioavailability, are essential for its effectiveness as a therapeutic agent. Research into ABCB1-IN-4 continues to explore its potential in overcoming multidrug resistance in cancer treatment, making it a subject of interest in medicinal chemistry and pharmacology.

ABCB1-IN-4

1500779-21-4: ABCB1-IN-4, with the CAS number 1500779-21-4, is a chemical compound that serves as an inhibitor of the ABCB1 protein, also known as P-glycoprotein. This protein plays a crucial role in the transport of various substances across cellular membranes, influencing drug absorption, distribution, and excretion. ABCB1-IN-4 is primarily studied for its potential applications in enhancing the efficacy of certain chemotherapeutic agents by inhibiting the efflux activity of P-glycoprotein, thereby increasing drug accumulation in cancer cells. The compound is characterized by its specific molecular structure, which allows it to interact with the binding site of the ABCB1 protein. Its pharmacological properties, including solubility, stability, and bioavailability, are essential for its effectiveness as a therapeutic agent. Research into ABCB1-IN-4 continues to explore its potential in overcoming multidrug resistance in cancer treatment, making it a subject of interest in medicinal chemistry and pharmacology.

<p>ABCB1-IN-4 (Compound C6z) is an orally active inhibitor of α-amylase and α-glucosidase, with IC50 values of 1.63 μM and 0.14 μM, respectively. It holds potential for diabetes research.</p>

CAS 1500779-21-4

ABCB1-IN-4

ABCB1-IN-4

Ref: TM-T205196