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CAS 150145-89-4

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(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

Description:
(S)-Alpha-methyl-4-carboxyphenylglycine, commonly referred to as (S)-AMPA, is an amino acid derivative that serves as a selective agonist for the AMPA receptor, a subtype of glutamate receptors in the central nervous system. This compound is characterized by its chiral nature, with the (S) configuration indicating its specific stereochemistry, which is crucial for its biological activity. It features a carboxylic acid functional group, contributing to its acidic properties, and an aromatic ring that enhances its interaction with biological targets. (S)-AMPA is soluble in water and exhibits a relatively high melting point, indicative of strong intermolecular interactions. Its role in neuropharmacology is significant, as it is involved in synaptic transmission and plasticity, making it a subject of interest in research related to cognitive functions and neurodegenerative diseases. Additionally, its structural features allow for potential modifications that could lead to the development of novel therapeutic agents targeting glutamatergic signaling pathways.
Formula:C10H10NO4
InChI:InChI=1/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)/p-1/t10-/m0/s1
SMILES:C[C@](c1ccc(cc1)C(=O)[O-])(C(=O)O)N
Synonyms:
  • (S)-Mcpg
  • S(+)-Alpha-Amino-4-Carboxy-Alpha-Methyl-Benzeneacetic Acid
  • 4-((1S)-1-Amino-1-Carboxyethyl)Benzoic Acid
  • (+)-Alpha-Methyl-4-Carboxyphenylglycine
  • (+)-Mcpg
  • (+-)-A-Methyl-4-Carboxyphenylglycine Glu Tamate Receptor An
  • (+)-Α-Methyl-4-Carboxyphenylglycine
  • 4-[(1S)-1-ammonio-1-carboxylatoethyl]benzoate
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