CAS 150238-87-2

H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2

Description:

The chemical substance with the name "H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2" is a peptide composed of a sequence of amino acids, specifically designed for various biochemical applications. Its structure includes a combination of hydrophobic, polar, and charged side chains, which contribute to its overall properties, such as solubility and stability in aqueous environments. The presence of multiple lysine residues suggests potential for strong interactions with negatively charged molecules, while the aromatic amino acids like phenylalanine and tryptophan may provide UV absorbance characteristics. This peptide may exhibit biological activity, potentially influencing cellular processes or serving as a model for studying protein interactions. The CAS number 150238-87-2 uniquely identifies this compound in chemical databases, facilitating research and application in fields such as biochemistry, pharmacology, and molecular biology. Its synthesis and characterization would typically involve techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry to confirm purity and structural integrity.

Formula: C₁₁₂H₁₇₈N₃₆O₂₇

Synonyms:

• H-Ala-Arg-Leu-Asp-Val-Ala-Ala-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-Nh2
• Arldvaaefrkkwnkwalsr-Nh2
• Arldvasefrkkwnkwalsr-Nh2
• Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-Nh2
• Pamp
• Pamp (1-20) Human
• Pamp Fragment 1-20 Human

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Proadrenomedullin, the precursor of adrenomedullin, contains a unique 20-residue sequence termed proadrenomedullin NH₂-terminal 20 peptide (PAMP). The i.v. administration of PAMP produces a rapid and strong hypotensive effect in anesthetized rats. It has been suggested, that PAMP functions as an inhibitory modulator of renal noradrenergic neurotransmission and plays an important role in regulating renal functions. Furthermore, it has been suggested that PAMP can act as an inhibitory regulator of adrenal catecholamine release in vivo and has a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice.

Formula: C₁₁₂H₁₇₈N₃₆O₂₇

Purity: 97.2%

Color and Shape: Whitish

Molecular weight: 2460.87

Ref: 01-4034490

Proadrenomedullin (1-20), human

CAS: 150238-87-2

Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.

Formula: C₁₁₂H₁₇₈N₃₆O₂₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 2460.84

Ref: TM-TP1490

PAMP (Human)

CAS: 150238-87-2

PAMP (human) is a peptide that binds to the G-protein coupled receptor, M3. It activates the ion channel and induces an influx of calcium ions into cells. This can lead to cell proliferation and differentiation, as well as increased blood flow in the brain. PAMP has been shown to inhibit ligand-induced activation of M3 receptors by competing with the natural ligands for binding sites on these receptors. It has also been shown to have high purity (>95%), and is currently under research for its use in various medical applications such as cancer therapy, pain management, and treatment of respiratory diseases.

Formula: C₁₁₂H₁₇₈N₃₆O₂₇

Purity: Min. 95%

Molecular weight: 2,460.8 g/mol

Ref: 3D-PAM-4291-V

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₁₂H₁₇₈N₃₆O₂₇

Molecular weight: 2,460.87 g/mol

Ref: 3D-PP51060

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

H-ARLDVASEFRKKWNKWALSR-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ARLDVASEFRKKWNKWALSR-NH2 is provided at greater that >95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ARLDVASEFRKKWNKWALSR-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ARLDVASEFRKKWNKWALSR-NH2 at the technical inquiry form on this page

Formula: C₁₁₂H₁₇₈N₃₆O₂₇

Purity: Min. 95%

Molecular weight: 2,460.87 g/mol

Ref: 3D-VAB-07852

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Custom research peptide; min purity 95%.

Formula: C₁₁₂H₁₇₈N₃₆O₂₇

Purity: Min. 95%

Molecular weight: 2,460.87 g/mol

Ref: 3D-PP17083

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Proadrenomedullin (1-20) is a polypeptide that is found in human plasma. It is a member of the vasoactive intestinal peptide family and has been shown to be involved in the regulation of vascular tone, blood pressure, and blood vessel permeability. Proadrenomedullin (1-20) also inhibits the production of proinflammatory cytokines such as tumor necrosis factor-alpha, interleukin-6, and interleukin-8. This compound has been shown to have antiviral activity against HIV and herpes simplex virus type 1. Proadrenomedullin (1-20) also functions as a growth factor for tumor cells.

Formula: C₁₁₂H₁₇₈N₃₆O₂₇

Purity: Min. 95%

Molecular weight: 2,460.84 g/mol

Ref: 3D-FP109402