CAS 150399-21-6

Balsalazide disodium dihydrate

Description:

Balsalazide disodium dihydrate is a pharmaceutical compound primarily used in the treatment of ulcerative colitis. It is a prodrug that is converted in the colon to its active form, 5-aminosalicylic acid (5-ASA), which exerts anti-inflammatory effects. The chemical formula of balsalazide disodium dihydrate reflects its disodium salt form, indicating the presence of two sodium ions and two water molecules associated with the compound. It is characterized by its relatively low solubility in water, which is beneficial for its targeted release in the gastrointestinal tract. The compound is typically administered orally and is known for its favorable safety profile, although it may cause side effects in some patients, such as gastrointestinal discomfort. Balsalazide disodium dihydrate is classified as a member of the aminosalicylate class of drugs, which are commonly used to manage inflammatory bowel diseases. Its mechanism of action involves the inhibition of leukotriene synthesis and scavenging of free radicals, contributing to its therapeutic efficacy in reducing inflammation in the colon.

Formula: C₁₇H₁₃N₃Na₂O₆

InChI: InChI=1/C17H15N3O6.2Na.2H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;;/h1-6,9,19H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;2*1H2/q;2*+1;;/p-2/b20-12-;;;;

InChI key: InChIKey=IBRSMMVMVMCYCS-MVIJUDHYSA-N

SMILES: C(O)(=O)C1=CC(/N=N/C2=CC=C(C(NCCC(O)=O)=O)C=C2)=CC=C1O.[Na].O

Synonyms:

• (E)-5-[[4-[[(2-CARBOXYETHYL)AMINO]CARBONYL]PHENYL]AZO]-2-HYDROXYBENZOIC ACID, DISODIUM SALT, dihydrate
• (E)-5-[[p-[(2-Carboxyethyl)carbamoyl]phenyl]azo]salicylic acid,disodium salt,dihydrate
• Balsalazide Disodium 2-Hydrate
• Balsalazide disodium hydrate
• Balsalazide disodium salt dihydrate
• Benzoic acid, 5-[(1E)-2-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]diazenyl]-2-hydroxy-, sodium salt, hydrate (1:2:2)
• Benzoic acid, 5-[(1E)-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]azo]-2-hydroxy-, disodium salt, dihydrate
• Benzoic acid, 5-[[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]azo]-2-hydroxy-, disodium salt, dihydrate, (E)-
• disodium (3Z)-3-({4-[(2-carboxylatoethyl)carbamoyl]phenyl}hydrazono)-6-oxocyclohexa-1,4-diene-1-carboxylate dihydrate
• Balsalazide disodium dihydrate
• disodium 3-[[4-[(2-carboxylatoethylamino)-oxomethyl]phenyl]hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienecarboxylate dihydrate
• Balsalazide disodium dihydrateQ: What is
• Balsalazide Disodium (200 mg)
• (E)-5-[[4-[[(2-Carboxyethyl)amino]-carbonyl]phenyl]azo-2-hydroxy-benzoic acid disodium salt
• Balsalazide disodium dihydrate Q: What is the storage condition of
• Balsalazide disodium dihydrate Q: What is the CAS Number of
• (3Z)-3-(2-{4-[(2-carboxyethyl)carbaMoyl]phenyl}hydrazin-1-ylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid
• BALSALZIDE DISODIUM
• BALOFLOXACIN
• Balsalzide disodium dihydrate
• Balsalazide disodium dihydrate Q: What are the applications of
• Balsalazide Disodium Salt Dihydrate&gt
• Balsalazide (sodium hydrate)
• 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic Acid Disodium Salt
• BALSALAZIDEDISODOUMSALT
• BALSALAZIDE SODIUM
• Balsalazie DisodiuM
• Balsalazide disodium

Balsalazide Disodium

CAS: 150399-21-6

Diazo-, azo-, or azoxy-compounds

Formula: C₁₇H₁₃N₃O₆Na₂·2H₂O

Color and Shape: Yellow Orange Crystalline Powder

Molecular weight: 401.05997

Ref: 45-1048255

Benzoic acid,5-[(1E)-2-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]diazenyl]-2-hydroxy-,sodium salt, hydrate (1:2:2)

CAS: 150399-21-6

Formula: C₁₇H₁₉N₃Na₂O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 439.3276

Ref: IN-DA00HXSN

Balsalazide disodium dihydrate

CAS: 150399-21-6

Balsalazide disodium dihydrate

Purity: ≥98%

Molecular weight: 437.31g/mol

Ref: 54-BUP18522

Balsalazide Disodium Salt Dihydrate

CAS: 150399-21-6

Balsalazide Disodium Salt Dihydrate

Purity: 98%

Molecular weight: 437.31g/mol

Ref: 54-OR1030335

Balsalazide disodium salt

CAS: 150399-21-6

Formula: C₁₇H₁₃N₃Na₂O₆·xH₂O

Purity: (HPLC) ≥ 98.0%

Color and Shape: Yellow crystalline powder

Molecular weight: 401.28 (anhydrous)

Ref: 7W-GP7647

Balsalazide disodium dihydrate

CAS: 150399-21-6

Balsalazide sodium hydrate treats mild-to-moderate ulcerative colitis; higher doses enhance remission maintenance; it's safe and effective.

Formula: C₁₇H₁₇N₃Na₂O₈

Purity: 98.95% - 99.49%

Color and Shape: Yellow To Orange Crystalline Powder

Molecular weight: 437.31

Ref: TM-T4615

Balsalazide Disodium Dihydrate

Controlled Product

CAS: 150399-21-6

Applications Balsalazide Disodium Dihydrate is an analogue of Sulfasalazine (S699084), A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-β-alanine. Anti-inflammatory (gastrointestinal).
References Prakash, A., et al.: Drugs, 56, 83 (1998), Coyne, C., et al.: Mol. Biol. Cell, 13, 3218 (2002), Willemsen, L., et al.: Clin. Exp. Immunol., 142, 275 (2005),

Formula: C₁₇H₁₃N₃Na₂O₆·2(H₂O)

Color and Shape: Neat

Molecular weight: 401.28 + x(18.02)

Ref: TR-B116295