CAS 150493-34-8

2-amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole

Description:

2-Amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole is a chemical compound characterized by its unique structure, which includes a benzimidazole core substituted with an amino group and a trifluoromethyl group. The presence of the 4-chlorobenzyl moiety enhances its lipophilicity and may influence its biological activity. This compound typically exhibits properties such as moderate solubility in organic solvents and potential reactivity due to the amino and trifluoromethyl groups. It may also display interesting pharmacological properties, making it a subject of interest in medicinal chemistry. The trifluoromethyl group is known to enhance metabolic stability and bioactivity, while the chlorine atom can affect the compound's electronic properties and interaction with biological targets. Overall, 2-amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole is a complex molecule with potential applications in drug development and research, particularly in areas related to its biological effects and mechanisms of action.

Formula: C₁₅H₁₁ClF₃N₃

InChI: InChI=1/C15H11ClF3N3/c16-11-4-1-9(2-5-11)8-22-13-6-3-10(15(17,18)19)7-12(13)21-14(22)20/h1-7H,8H2,(H2,20,21)

SMILES: c1cc(ccc1Cn1c2ccc(cc2[nH]c1=N)C(F)(F)F)Cl

Synonyms:

• Ns 638
• 1-((4-Chlorophenyl)methyl)-5-(trifluoromethyl)-1H-benzimidazol-2-amine
• 1H-Benzimidazol-2-amine, 1-((4-chlorophenyl)methyl)-5-(trifluoromethyl)-
• 1-(4-chlorobenzyl)-5-(trifluoromethyl)-1H-benzimidazol-2-amine

1H-Benzimidazol-2-amine, 1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)-

CAS: 150493-34-8

Formula: C₁₅H₁₁ClF₃N₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 325.7161

Ref: IN-DA001MND

NS-638

CAS: 150493-34-8

NS-638

Purity: ≥98%

Molecular weight: 325.72g/mol

Ref: 54-BUP05827

NS-638

CAS: 150493-34-8

NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).

Formula: C₁₅H₁₁ClF₃N₃

Purity: 98.44%

Color and Shape: Solid

Molecular weight: 325.72

Ref: TM-T3543