CAS 150566-71-5

S-Amlodipine

Description:

S-Amlodipine is a calcium channel blocker primarily used in the treatment of hypertension and angina. It is the S-enantiomer of amlodipine, which means it has a specific three-dimensional arrangement that contributes to its pharmacological activity. This compound works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. S-Amlodipine is typically administered in oral form and has a long half-life, allowing for once-daily dosing. It is characterized by its relatively high solubility in organic solvents and low solubility in water, which can influence its absorption and bioavailability. The substance is generally well-tolerated, with common side effects including peripheral edema, headache, and fatigue. Its chemical structure includes a dihydropyridine ring, which is essential for its activity as a calcium channel blocker. Overall, S-Amlodipine is an important medication in cardiovascular therapy, providing effective management of blood pressure and angina symptoms.

Formula: C₂₆H₃₁ClN₂O₈S

InChI: InChI=1S/C20H25ClN2O5.C6H6O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;7-10(8,9)6-4-2-1-3-5-6/h5-8,17,23H,4,9-11,22H2,1-3H3;1-5H,(H,7,8,9)/t17-;/m0./s1

InChI key: InChIKey=ZPBWCRDSRKPIDG-LMOVPXPDSA-N

SMILES: C(OCC)(=O)C=1[C@H](C(C(OC)=O)=C(C)NC1COCCN)C2=C(Cl)C=CC=C2.S(=O)(=O)(O)C1=CC=CC=C1

Synonyms:

• (-)-Amlodipine besylate
• (S)-Amlodipine besylate
• 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-, benzenesulfonate (1:1)
• 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-, monobenzenesulfonate
• Levamlodipine besylate
• LEVAMLODIPINE BESYLATE，S-Amlodipine

3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-, benzenesulfonate (1:1)

CAS: 150566-71-5

Formula: C₂₆H₃₁ClN₂O₈S

Purity: 97%

Color and Shape: Solid

Molecular weight: 567.0509

Ref: IN-DA001MQ9

Levamlodipine besylate

CAS: 150566-71-5

Levamlodipine besylate

Purity: ≥98%

Molecular weight: 567.05g/mol

Ref: 54-BUP06913

Levamlodipine besylate

CAS: 150566-71-5

Levamlodipine besylate, or S-amlodipine (CAS 103129-82-4), is the active enantiomer of amlodipine, used to treat hypertension and angina.

Formula: C₂₆H₃₁ClN₂O₈S

Purity: 99.78% - 99.79%

Color and Shape: Solid

Molecular weight: 567.05

Ref: TM-T4284

S-Amlodipine Besylate

CAS: 150566-71-5

Formula: C₂₀H₂₅ClN₂O₅C₆H₆O₃S

Molecular weight: 408.9 : 158.1

Ref: ST-EA-CP-A5033

Levamlodipine Besylate

Controlled Product

CAS: 150566-71-5

Formula: C₂₀H₂₅ClN₂O₅·C₆H₆O₃S

Color and Shape: Off-White To Light Yellow

Molecular weight: 567.051

Ref: TR-L246725

Levamlodipine besylate

CAS: 150566-71-5

Levamlodipine besylate is a drug used to treat high blood pressure. It belongs to the class of calcium channel blockers. Levamlodipine besylate works by blocking calcium flow through the muscle cells in your heart and blood vessels, which causes them to relax. This decreases the resistance in your arteries, which reduces blood pressure. There are many drugs that can cause a reaction if taken with levamlodipine besylate, including losartan (Cozaar). The most common side effect reported is headache, but other possible side effects include dizziness and tiredness. If you experience any of these symptoms or other serious side effects while taking this medication, contact your doctor immediately.

Formula: C₂₀H₂₅ClN₂O₅•C₆H₆O₃S

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 567.05 g/mol

Ref: 3D-FL34051