CAS 150671-05-9

ceratotoxin B

Description:

Ceratotoxin B is a potent neurotoxin produced by certain species of the venomous frog, specifically from the genus Corythomantis. It is classified as a peptide toxin and is known for its ability to disrupt neurotransmission by targeting ion channels, particularly those involved in the regulation of sodium and potassium ions. This disruption can lead to paralysis and other severe physiological effects in affected organisms. Ceratotoxin B exhibits high specificity and affinity for its targets, making it a subject of interest in pharmacological research, particularly in the development of novel therapeutic agents. The structure of ceratotoxin B includes a series of amino acids that contribute to its biological activity and stability. Its unique properties also make it a valuable tool for studying ion channel function and the mechanisms of neurotoxicity. As with many toxins, safety precautions are essential when handling ceratotoxin B due to its potential harmful effects on human health and the environment.

Formula: C₁₃₅H₂₃₅N₃₅O₃₂

InChI: InChI=1/C135H235N35O32/c1-23-76(12)106(165-117(183)88(142)70-171)128(194)144-69-104(174)154-99(71-172)125(191)150-83(19)113(179)160-95(67-87-44-27-26-28-45-87)124(190)159-93(50-33-39-59-140)122(188)157-91(48-31-37-57-138)120(186)149-84(20)116(182)162-97(65-73(6)7)132(198)168-61-41-52-100(168)126(192)164-105(75(10)11)130(196)151-85(21)111(177)156-92(49-32-38-58-139)121(187)158-94(51-34-40-60-141)123(189)166-107(77(13)24-2)129(195)143-68-103(173)153-89(46-29-35-55-136)118(184)147-79(15)109(175)145-81(17)114(180)161-96(64-72(4)5)133(199)169-62-42-53-101(169)127(193)167-108(78(14)25-3)131(197)152-86(22)112(178)155-90(47-30-36-56-137)119(185)148-80(16)110(176)146-82(18)115(181)163-98(66-74(8)9)134(200)170-63-43-54-102(170)135(201)202/h26-28,44-45,72-86,88-102,105-108,171-172H,23-25,29-43,46-71,136-142H2,1-22H3,(H,143,195)(H,144,194)(H,145,175)(H,146,176)(H,147,184)(H,148,185)(H,149,186)(H,150,191)(H,151,196)(H,152,197)(H,153,173)(H,154,174)(H,155,178)(H,156,177)(H,157,188)(H,158,187)(H,159,190)(H,160,179)(H,161,180)(H,162,182)(H,163,181)(H,164,192)(H,165,183)(H,166,189)(H,167,193)(H,201,202)/t76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,105-,106-,107-,108-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=NCC(=N[C@@H](CO)C(=N[C@@H](C)C(=N[C@@H](Cc1ccccc1)C(=N[C@@H](CCCCN)C(=N[C@@H](CCCCN)C(=N[C@@H](C)C(=N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=N[C@@H](C(C)C)C(=N[C@@H](C)C(=N[C@@H](CCCCN)C(=N[C@@H](CCCCN)C(=N[C@@H]([C@@H](C)CC)C(=NCC(=N[C@@H](CCCCN)C(=N[C@@H](C)C(=N[C@@H](C)C(=N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=N[C@@H]([C@@H](C)CC)C(=N[C@@H](C)C(=N[C@@H](CCCCN)C(=N[C@@H](C)C(=N[C@@H](C)C(=N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C([C@H](CO)N)O

Ceratotoxin B

CAS: 150671-05-9

Ceratotoxins B, an antibacterial peptide, is produced by sexually mature females of Ceratitis capitata (medfly).

Formula: C₁₃₅H₂₃₅N₃₅O₃₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 2860.53

Ref: TM-TP1556