CAS 150737-17-0

(9cis)-4-hydroxyretinoic acid

Description:

(9-cis)-4-hydroxyretinoic acid is a derivative of retinoic acid, which is a metabolite of vitamin A and plays a crucial role in various biological processes, including vision, growth, and differentiation of cells. This compound is characterized by its specific stereochemistry, with the "9-cis" configuration indicating the position of a double bond in the carbon chain, which influences its biological activity and receptor binding. The presence of a hydroxyl group at the 4-position enhances its solubility and reactivity. (9-cis)-4-hydroxyretinoic acid is known to interact with retinoic acid receptors (RARs), which are nuclear receptors that regulate gene expression in response to retinoids. This compound has been studied for its potential therapeutic applications, particularly in dermatology and oncology, due to its ability to modulate cell growth and differentiation. Its stability, solubility, and biological activity make it a significant compound in research related to developmental biology and cancer treatment.

Formula: C₂₀H₂₈O₃

InChI: InChI=1/C20H28O3/c1-14(7-6-8-15(2)13-19(22)23)9-10-17-16(3)18(21)11-12-20(17,4)5/h6-10,13,18,21H,11-12H2,1-5H3,(H,22,23)/b8-6+,10-9+,14-7-,15-13+

Synonyms:

• All-Trans-4-Hydroxyretinoic Acid

Retinoic acid, 4-hydroxy-, 9-cis-

CAS: 150737-17-0

Formula: C₂₀H₂₈O₃

Color and Shape: Solid

Molecular weight: 316.4345

Ref: IN-DA001MTJ

4-Hydroxy-9-cis-Retinoic Acid

CAS: 150737-17-0

Formula: C₂₀H₂₈O₃

Color and Shape: Yellow Solid

Molecular weight: 316.44

Ref: 4Z-T-114008

rac 4-Hydroxy-9-cis-retinoic acid

CAS: 150737-17-0

9-cis-Retinoic acid is a retinoid that is found in the human body. It can be extracted from the cells of animals or plants and purified by using an organic solvent, such as hexane. 9-cis-Retinoic acid can also be synthesized by using a validated hplc method. Analysts use this compound to measure conjugate acids, hydroxy acids, and other compounds related to endogenous metabolism. It is often used as a buffering agent for specific applications.

Formula: C₂₀H₂₈O₃

Purity: Min. 95%

Molecular weight: 316.43 g/mol

Ref: 3D-FR27460

rac 4-Hydroxy-9-cis-retinoic Acid

Controlled Product

CAS: 150737-17-0

Applications A metabolite of 9-cis-Retinoic acid (R245000).
References Omiecinski, C., et al.: Cancer Res., 50, 4315 (1990), Chapman, D., et al.: Biochem. Pharmacol., 48, 1807 (1994), White, J., et al.: J. Biol. Chem., 271, 29922 (1996), Chen, H., et al.: Drug Metab. Dispos., 28, 1051 (2000),

Formula: C₂₀H₂₈O₃

Color and Shape: Neat

Molecular weight: 316.43

Ref: TR-H953310

4-Hydroxy-9-Cis-Retinoic Acid

CAS: 150737-17-0

Formula: C₂₀H₂₈O₃

Molecular weight: 316.44

Ref: ST-EA-CP-I25010