CAS 150737-18-1

9-cis-4-Oxoretinoic acid

Description:

9-cis-4-Oxoretinoic acid is a derivative of retinoic acid, which is a metabolite of vitamin A and plays a crucial role in various biological processes, including vision, cell growth, and differentiation. This compound is characterized by its specific geometric configuration, which influences its biological activity and interaction with retinoic acid receptors. It features a carboxylic acid functional group, contributing to its solubility in polar solvents and its reactivity in biochemical pathways. The "9-cis" designation indicates the presence of a cis double bond at the ninth carbon position, which is significant for its binding affinity to nuclear receptors. 9-cis-4-Oxoretinoic acid is involved in the regulation of gene expression and has been studied for its potential therapeutic applications in dermatology and oncology. Its stability and reactivity can be influenced by environmental factors such as light and pH, making it important to handle and store it under appropriate conditions to maintain its efficacy.

Formula: C₂₀H₂₆O₃

InChI: InChI=1S/C20H26O3/c1-14(7-6-8-15(2)13-19(22)23)9-10-17-16(3)18(21)11-12-20(17,4)5/h6-10,13H,11-12H2,1-5H3,(H,22,23)/b8-6+,10-9+,14-7-,15-13+

InChI key: InChIKey=GGCUJPCCTQNTJF-NAXRMXIQSA-N

SMILES: C(=C/C(=C\C=C\C(=C\C(O)=O)\C)/C)\C=1C(C)(C)CCC(=O)C1C

Synonyms:

• (2E,4E,6Z,8E)-4-Keto-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic Acid
• (9Cis)-4-Oxoretinoic Acid
• 4-Keto-9-cis-tretinoin
• 4-Oxo-9-cis-Retinoic Aci
• 4-Oxo-9-cis-Retinoic Acid
• 9-cis-4-Oxoretinoic acid
• Retinoic acid, 4-oxo-, 9-cis-
• 4-keto-9-cis-Retinoic acid

4-Keto 9-cis Retinoic Acid

CAS: 150737-18-1

Formula: C₂₀H₂₆O₃

Color and Shape: Solid

Molecular weight: 314.4186

Ref: IN-DA001MTI

4-Oxo-9-cis-Retinoic acid

CAS: 150737-18-1

Formula: C₂₀H₂₆O₃

Color and Shape: Yellow Solid

Molecular weight: 314.43

Ref: 4Z-T-114007

4-Keto 9-cis Retinoic Acid

Controlled Product

CAS: 150737-18-1

Stability Light and Temperature Sensitive
Applications A metabolite of Retinoic acid.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hoyos, B., et al.: J. Exp. Med.,192, 835 ( 2000), Braungart, E., et al.: J. Invest. Dermatol.,116, 778 (2001), Fray, M., et al.: J. Med. Chem., 46, 3514 (2003), Ha, M., et al.: Exp. Dermatol., et al.: 13, 543 (2004),

Formula: C₂₀H₂₆O₃

Color and Shape: Yellow

Molecular weight: 314.42

Ref: TR-K204960

4-Keto 9-cis-Retinoic Acid-13C-d3

Controlled Product

CAS: 150737-18-1

Formula: CC₁₉D₃H₂₃O₃

Color and Shape: Neat

Molecular weight: 318.43

Ref: TR-K204961

4-Oxo-9-Cis Retinoic Acid

CAS: 150737-18-1

Formula: C₂₀H₂₆O₃

Molecular weight: 314.43

Ref: ST-EA-CP-I25016