CAS 1507370-78-6

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl-

Description:

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl- is a complex organic compound characterized by its pyrazolo-pyrimidine core structure, which is known for its potential biological activity. This compound features a piperazine moiety, which is often associated with pharmacological properties, and a difluorophenyl group that may enhance its lipophilicity and biological interactions. The presence of a methoxyethoxy substituent suggests increased solubility and potential for improved pharmacokinetic profiles. The compound's structure indicates it may interact with various biological targets, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its CAS number, 1507370-78-6, allows for precise identification and retrieval of information regarding its properties, synthesis, and applications in scientific literature. Overall, this compound exemplifies the intricate design often employed in drug discovery to optimize efficacy and selectivity.

Formula: C₁₉H₂₂F₂N₆O₃

Synonyms:

• 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl-

G-631

CAS: 1507370-78-6

G-631 acts as a selective tankyrase inhibitor, effectively hindering tankyrase auto-PARsylation (poly ADP ribosylation) at an IC 50 of 7 nM and suppressing the Wnt signaling pathway. This compound also demonstrates favorable pharmacokinetic properties in mice.

Formula: C₁₉H₂₂F₂N₆O₃

Color and Shape: Solid

Molecular weight: 420.41

Ref: TM-T200085