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CAS 150821-39-9

:

9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxorapamycin

Description:
9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxorapamycin, identified by its CAS number 150821-39-9, is a complex macrolide compound derived from rapamycin, which is known for its immunosuppressive and anti-proliferative properties. This substance features multiple functional groups, including epoxy, hydroxy, and keto groups, contributing to its biological activity. The presence of deepoxy and deoxy modifications indicates alterations in the molecular structure that may enhance its pharmacological profile. Typically, compounds of this nature exhibit significant interactions with cellular pathways, particularly those involved in cell growth and immune response modulation. The structural intricacies of this compound suggest potential applications in therapeutic contexts, particularly in oncology and transplant medicine. However, detailed studies on its specific biological activities, mechanisms of action, and safety profiles are essential for understanding its full potential and implications in clinical settings. As with many derivatives of rapamycin, it may also exhibit a range of side effects and interactions that warrant careful consideration in therapeutic use.
Formula:C51H79NO13
InChI:InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-32(3)48(57)51(60,65-38)50(59)52-23-15-14-18-39(52)49(58)64-43(34(5)26-37-20-22-40(53)44(27-37)62-9)29-41(54)33(4)25-36(7)46(56)47(63-10)45(55)35(6)24-30/h11-13,16-17,25,30,32-35,37-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,36-25+/t30-,32-,33-,34-,35-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51?/m1/s1
InChI key:InChIKey=PZJRKKHZEUDQHR-XASJUNOOSA-N
SMILES:O=C1N2[C@](C(=O)O[C@]([C@@H](C[C@H]3C[C@@H](OC)[C@H](O)CC3)C)(CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C(\C)/[C@@H](OC)C[C@]4(OC1(O)C(=O)[C@H](C)CC4)[H])[H])(CCCC2)[H]
Synonyms:
  • 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxorapamycin
  • Rapamycin, 9,14-deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxo-
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Found 3 products.
  • Rapamycin Impurity 6
    TLC
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    Rapamycin Impurity 6

    CAS:
    Formula:C51H79NO13
    Molecular weight:914.19

    Ref: 4Z-R-1812

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  • 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxorapamycin (>80%)
    TRC
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    9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxorapamycin (>80%)

    Controlled Product
    CAS:

    Applications 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxorapamycin can be prepared as an immunosuppressant.
    References Hughes, P.F.: U.S. 4 pp. Patent 1993 CODEN:USXXAM

    Formula:C51H79NO13
    Purity:>80%
    Color and Shape:Neat
    Molecular weight:914.17

    Ref: TR-D228588

    10mg
    2,301.00€
    2500µg
    717.00€
  • Sirolimus Isomer C
    Standalix
    + Info

    Sirolimus Isomer C

    CAS:
    Formula:C51H79NO13
    Molecular weight:914.2

    Ref: ST-EA-CP-R26007

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