CAS 15087-01-1

1,3,5[10]-ESTRATRIEN-3-OL-17-ONE 3-GLUCURONIDE SODIUM SALT

Description:

1,3,5[10]-Estratrien-3-ol-17-one 3-glucuronide sodium salt, with CAS number 15087-01-1, is a chemical compound that belongs to the class of steroid hormones, specifically a glucuronide conjugate of estradiol. This compound is characterized by its steroidal structure, which includes a phenolic hydroxyl group and a glucuronide moiety that enhances its solubility and facilitates excretion. The sodium salt form indicates that it is ionized, which can influence its bioavailability and pharmacokinetics. Typically, glucuronides are formed in the liver through the process of glucuronidation, which is a major pathway for the metabolism of various endogenous and exogenous compounds. This compound may play a role in the regulation of estrogenic activity in the body and is often studied in the context of hormonal therapies and endocrine function. Its properties, such as solubility, stability, and biological activity, are influenced by the presence of the glucuronide group and the sodium ion.

Formula: C₂₄H₂₉NaO₈

InChI: InChI=1/C24H30O8.Na/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30;/h3,5,10,14-16,18-21,23,26-28H,2,4,6-9H2,1H3,(H,29,30);/q;+1/p-1/t14-,15-,16+,18+,19+,20-,21+,23-,24+;/m1./s1

SMILES: CC12CCC3c4ccc(cc4CCC3C1CCC2=O)OC1C(C(C(C(C(=O)O)O1)O)O)O.[Na]

Synonyms:

• Estrone-3-(Beta-D-Glucuronide Sodium Salt)
• Estrone-3-Glucuronide Sodium Salt
• Estrone Beta-D-Glucuronide Sodium Salt
• Estrone Glucuronide, Sodium Salt
• 3-Hydroxy-1,3,5[10]-Estratrien-17-One 3-Glucuronide Sodium Salt
• 1,3,5(10)-Estratrien-3-Ol-17-One Glucosiduronate, Sodium Salt
• 1,3,5(10)-Estratrien-3-Ol-17-One 3(O->1Beta)-D-Glucopyranosiduronic Acid Sodium Salt
• sodium (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl]oxy}tetrahydro-2H-pyran-2-carboxylate (non-preferred name)

Estrone-3-Glucuronide sodium

CAS: 15087-01-1

Estrone-3-Glucuronide sodium is a coupled metabolite of estrone, which is formed in the liver by UDP-glucuronyltransferase through glucuronide coupling.

Formula: C₂₄H₂₉NaO₈

Purity: >99.99%

Color and Shape: Soild

Molecular weight: 468.47

Ref: TM-T204086

Estrone-3-Glucuronide sodium

CAS: 15087-01-1

Estrone-3-Glucuronide sodium

Purity: ≥98%

Molecular weight: 468.47g/mol

Ref: 54-BUP21134

Estrone b-D-glucuronide sodium salt

CAS: 15087-01-1

Formula: C₂₄H₂₉NaO₈

Molecular weight: 468.47

Ref: 7W-GC1179

Estrone b-D-Glucuronide Sodium Salt (>97% by HPLC)

Controlled Product

CAS: 15087-01-1

Applications A metabolite of 17β -Estradiol (E888000).
References Cekan, S., et al.: J. Steroid Biochem., 27, 95 (1989), Martin, R., et al.: Clin. Chem., 46, 100 (2000), Blackwell, L., et al.: Steroids, 68, 465 (2003)

Formula: C₂₄H₂₉O₈·Na

Purity: >97% by HPLC

Color and Shape: White To Light Brown

Molecular weight: 468.47

Ref: TR-E889055

Estrone b-D-glucuronide sodium salt

CAS: 15087-01-1

Estrone b-D-glucuronide sodium salt (EBGG) is a steroid hormone that is synthesized in the ovaries. EBGG has been shown to be effective against bacterial vaginosis and polycystic ovarian syndrome. It is not active against other types of vaginal infections, such as yeast vaginitis or candida vulvovaginitis. EBGG has also been used to treat infertility in women, with promising results. The compound may work by increasing the metabolic rate and suppressing the production of progesterone and testosterone, which are important for fertility. EBGG binds to an estrogen receptor on cells in the uterus, stimulating the growth of uterine tissue and increasing blood flow to the uterus. EBGG binds to a specific site on the surface of cells called a monoclonal antibody, which can inhibit cell proliferation. This binding leads to an increase in progesterone receptor expression on uterine cells and inhibits the production of progesterone receptors on breast cancer

Formula: C₂₄H₂₉O₈·Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 468.47 g/mol

Ref: 3D-ME11970

Estrone β-D-Glucuronide Sodium Salt

CAS: 15087-01-1

Formula: C₂₄H₂₉O₈Na

Molecular weight: 445.49 : 23

Ref: ST-EA-CP-E30031