CAS 150915-40-5: Tirofiban hydrochloride monohydrate
Description:Tirofiban hydrochloride monohydrate is a synthetic compound primarily used as an antiplatelet agent in the management of acute coronary syndromes. It functions as a reversible antagonist of the glycoprotein IIb/IIIa receptor on platelets, thereby inhibiting platelet aggregation and reducing the risk of thrombus formation. This compound appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration via intravenous routes. Its molecular formula includes a hydrochloride salt and a monohydrate form, indicating the presence of water molecules in its crystalline structure. Tirofiban is characterized by its relatively short half-life, necessitating continuous infusion for effective therapeutic action. The pharmacokinetics of tirofiban involve rapid absorption and distribution, with metabolism primarily occurring in the liver. It is essential to monitor patients for potential side effects, including bleeding complications, due to its mechanism of action. Overall, tirofiban hydrochloride monohydrate plays a crucial role in acute cardiac care, enhancing patient outcomes in high-risk scenarios.
Formula:C22H36N2O5S·ClH·H2O
InChI:InChI=1S/C22H36N2O5S.ClH.H2O/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18;;/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26);1H;1H2/t21-;;/m0../s1
InChI key:InChIKey=HWAAPJPFZPHHBC-FGJQBABTSA-N
SMILES:Cl.O=C(O)C(NS(=O)(=O)CCCC)CC1=CC=C(OCCCCC2CCNCC2)C=C1.O
- Synonyms:
- (2R)-3-(butylsulfonyl)-2-{4-[4-(piperidin-4-yl)butoxy]benzyl}propanoic acid hydrochloride hydrate
- (2S)-2-(Butylsulfonylamino)-3-[4-[4-(4-Piperidyl)Butoxy]Phenyl]Propanoic Acid Hydrochloride
- (2S)-2-(Butylsulfonylamino)-3-[4-[4-(4-Piperidyl)Butoxy]Phenyl]Propanoic Acid Hydrochloride Monohydrate
- 1-[3-(2,4,6-Trimethoxybenzoyl)propyl]pyrrolidinium chloride
- <span class="text-smallcaps">L</span>-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, hydrochloride, hydrate (1:1:1)
- <span class="text-smallcaps">L</span>-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, monohydrochloride, monohydrate
- N-(Butylsulfonyl)-O-(4-(4-Piperidinyl)Butyl)-L-Tyrosine Hydrochloride
- N-(Butylsulfonyl)-O-(4-(4-Piperidinyl)Butyl)-L-Tyrosine Hydrochloride Monohydrate
- N-(Butylsulfonyl)-O-[4-(4-Piperidynyl)Butyl]-L-Tyrosine Hydrochloride
- N-(Butylsulfonyl)-O-[4-(4-Piperidynyl)Butyl]-L-Tyrosine Hydrochloride Monohydrate
- See more synonyms
- N-(Butylsulfonyl)-O-[4-Pyridin-4-Yl]Butyl]-L-Tyrosine Hydrochloride
- N-(Butylsulfonyl)-O-[4-Pyridin-4-Yl]Butyl]-L-Tyrosine Hydrochloride Monohydrate
- N-(butylsulfonyl)-O-[4-(piperidin-4-yl)butyl]-L-tyrosine hydrochloride (1:1)
- N-(butylsulfonyl)-O-[4-(piperidin-4-yl)butyl]-L-tyrosine hydrochloride hydrate
- N-Butylsulfonyl-O-(4-(4-Pyridinyl)Butyl)-L-Tyrosine Hydrochloride
- N-Butylsulfonyl-O-(4-(4-Pyridinyl)Butyl)-L-Tyrosine Hydrochloride Monohydrate
- Tirofiban HCL
- Tirofiban HCl monohydrate
- Tirofiban hydrochloride
- L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, monohydrochloride, monohydrate
- L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, hydrochloride, hydrate (1:1:1)
- Tirofiban hydrochloride monohydrate