CAS 150956-92-6

Dnp-Pro-.beta.-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2

Description:

Dnp-Pro-.beta.-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2, with the CAS number 150956-92-6, is a synthetic peptide that exhibits characteristics typical of peptide compounds. It consists of a sequence of amino acids, including proline, alanine, glycine, cysteine (with a methyl group), histidine, and lysine (with a N-methyl-2-aminobenzoyl modification). This peptide is likely to have a specific three-dimensional structure influenced by the presence of cyclic and modified amino acids, which can affect its biological activity and stability. The presence of cysteine suggests potential for disulfide bond formation, which can further stabilize the peptide's conformation. The N-terminal modification with a Dinitrophenyl (Dnp) group may enhance its solubility and facilitate detection in analytical applications. Peptides like this one are often studied for their roles in biological systems, potential therapeutic applications, or as tools in biochemical research. However, specific properties such as solubility, stability, and biological activity would depend on the context of use and the environment in which the peptide is studied.

Formula: C₄H₆₈N₁₄O₁₂S

Synonyms:

• Mmp-1/Mmp-9 Substrate, Fluorogenic

Dnp-Pro-β-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂

CAS: 150956-92-6

Efficient fluorogenic substrate for two matrix metalloproteinases: interstitial collagenase (MMP-1) and gelatinase (MMP-9). Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-amide has favorable solubility characteristics. Both enzymes cleave this substrate between Gly and Cys(Me) (Smc), liberating a cleavage product with a fluorescence signal suitable for inhibitor screening and determining Ki values. The major advantage of this FRET substrate is its adaptability to filters commonly available on commercial plate readers (excitation at 365 nm and emission at 450 nm).

Formula: C₄₉H₆₈N₁₄O₁₂S

Purity: 95.6%

Color and Shape: Yellow

Molecular weight: 1077.23

Ref: 01-4025472

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2

CAS: 150956-92-6

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).

Formula: C₄₉H₆₈N₁₄O₁₂S

Color and Shape: Solid

Molecular weight: 1077.22

Ref: TM-T36360

Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2

CAS: 150956-92-6

Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2 is a versatile building block that can be used in the synthesis of complex compounds, research chemicals and reagents. It has been shown to be useful in the synthesis of high quality, useful intermediates and reaction components. Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N--Me--Abz)-NH2 is also a useful scaffold for the preparation of biologically active compounds.

Formula: C₄₉H₆₈N₁₄O₁₂S

Purity: Min. 95%

Molecular weight: 1,077.22 g/mol

Ref: 3D-FD110910

Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(NMa)-NH2

CAS: 150956-92-6

Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(NMa)-NH2 is a synthetic peptide substrate that is used in the study of proteolytic enzymes. It has been shown to be an inhibitor of collagenase, MMPs, and stromelysin. This product can be used to determine the kinetic parameters for these enzymes. Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(NMa)-NH2 can be used as a substrate for enzyme catalysis studies, as well as for research on cancer and collagen.

Formula: C₄₉H₆₈N₁₄O₁₂S

Purity: Min. 95%

Molecular weight: 1,077.24 g/mol

Ref: 3D-SDP-3815-PI