CAS 1510-21-0

Cholesteryl hemisuccinate

Description:

Cholesteryl hemisuccinate is a derivative of cholesterol, characterized by the presence of a hemisuccinate group attached to the cholesterol backbone. This compound is typically used in biochemical and pharmaceutical applications, particularly in drug delivery systems and as a component in liposomal formulations. It exhibits amphiphilic properties, which means it has both hydrophilic (water-attracting) and hydrophobic (water-repelling) characteristics, making it useful for forming lipid bilayers and micelles. Cholesteryl hemisuccinate can enhance the solubility of hydrophobic drugs and facilitate their transport across biological membranes. Additionally, it is known for its ability to form stable complexes with various biomolecules, which can be beneficial in targeted drug delivery. The compound is generally considered to be biocompatible, making it suitable for use in pharmaceutical applications. Its structural features contribute to its role in modifying membrane properties and influencing cellular interactions, which are critical in the development of novel therapeutic strategies.

Formula: C₃₁H₅₀O₄

InChI: InChI=1S/C31H50O4/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33)/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1

InChI key: InChIKey=WLNARFZDISHUGS-MIXBDBMTSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C[C@@H](OC(CCC(O)=O)=O)CC2)[H])[H]

Synonyms:

• 3-(3-Cholesteryloxycarbonyl)propionic acid
• 3-Cholesteryloxycarbonylpropanoic acid
• 3-[(Cholest-5-en-3β-yl)oxycarbonyl]propionic acid
• 4-(Cholest-5-En-3-Yloxy)-4-Oxobutanoic Acid
• 4-[(3Beta)-Cholest-5-En-3-Yloxy]-4-Oxobutanoic Acid
• Chems
• Cholest-5-en-3-ol (3β)-, 3-(hydrogen butanedioate)
• Cholest-5-en-3-ol (3β)-, hydrogen butanedioate
• Cholesterol hemisuccinate
• Cholesterol hydrogen succinate
• Cholesterol monosuccinate
• Cholesteryl Hemisuccinate
• Cholesteryl hydrogen succinate
• Cholesteryl hydrogen succinate Cholesteryl hemisuccinate
• Cholesteryl monosuccinate
• Mono(cholesteryl) succinate
• Succinate cholesterol monoester

Cholesterol Hydrogen Succinate

CAS: 1510-21-0

Formula: C₃₁H₅₀O₄

Purity: >97.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 486.74

Ref: 3B-C0674

Cholest-5-en-3-ol (3β)-, 3-(hydrogen butanedioate)

CAS: 1510-21-0

Formula: C₃₁H₅₀O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 486.7263

Ref: IN-DA001N0N

Cholesteryl Hemisuccinate

CAS: 1510-21-0

Cholesteryl Hemisuccinate

Purity: 97%

Molecular weight: 486.73g/mol

Ref: 54-OR1030148

Cholesteryl Hemisuccinate

CAS: 1510-21-0

Cholesteryl Hemisuccinate

Purity: ≥98%

Molecular weight: 486.73g/mol

Ref: 54-BUP18726

Cholesteryl Hemisuccinate

CAS: 1510-21-0

Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective,

Formula: C₃₁H₅₀O₄

Purity: 99.61% - 99.98%

Color and Shape: White Powder

Molecular weight: 486.73

Ref: TM-T67509

Cholesterol hydrogen succinate

Controlled Product

CAS: 1510-21-0

Cholesterol hydrogen succinate is a cholesterol derivative that inhibits the activity of various receptors, including the LDL-receptor which is involved in the uptake of cholesterol from the blood. It also has inhibitory properties against infectious diseases and can be used as an experimental model for coronary heart disease. Cholesterol hydrogen succinate has been shown to inhibit the phase transition temperature (Tc) of human serum. This drug also possesses anti-oxidative properties and has been shown to have protective effects on mitochondrial membrane potential. The biological properties of this compound include its ability to induce hemisuccinate formation by hydrolyzing cholesteryl esters and inhibit endoxifen activity.

Formula: C₃₁H₅₀O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 486.73 g/mol

Ref: 3D-FC61971

Cholesteryl Hemisuccinate

Controlled Product

CAS: 1510-21-0

Applications Cholesteryl Hemisuccinate is an oxidation product of polyunsaturated fatty acid of cholesterol that alters lysosome structure and functions and induces proinflammatory cytokine production in macrophages.
References Domingues, N., et al.; Biochim. Biophys. Acta, Mol. Cell Biol. Lipids, 1862, 210 (2017)

Formula: C₃₁H₅₀O₄

Color and Shape: White To Off-White

Molecular weight: 486.73

Ref: TR-C432586