CAS 151096-09-2

Moxifloxacin

Description:

Moxifloxacin is a synthetic fluoroquinolone antibiotic that exhibits broad-spectrum antibacterial activity. It is primarily used to treat respiratory tract infections, skin infections, and certain types of bacterial infections. The chemical formula of moxifloxacin is C21H24FN3O4, and it features a bicyclic structure that includes a quinolone core, which is essential for its antimicrobial properties. Moxifloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair, thereby preventing bacterial growth. It is characterized by its high oral bioavailability and a relatively long half-life, allowing for once-daily dosing. Moxifloxacin is also known for its favorable pharmacokinetic profile, including good tissue penetration and the ability to reach high concentrations in respiratory tissues. However, like other fluoroquinolones, it may be associated with side effects such as gastrointestinal disturbances, central nervous system effects, and potential tendon damage. Caution is advised in its use, particularly in certain populations, including those with a history of tendon disorders or in pediatric patients.

Formula: C₂₁H₂₄FN₃O₄

InChI: InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1

InChI key: InChIKey=FABPRXSRWADJSP-MEDUHNTESA-N

SMILES: O(C)C1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3C[C@]4([C@@](C3)(NCCC4)[H])[H])C5CC5

Synonyms:

• (1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• (4αS-cis)-1-Cydopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-y1)-4-oxo-3-quinolinecarboxylic acid
• 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid
• 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-, (4aS-cis)-
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-
• 6H-Pyrrolo[3,4-b]pyridine, 3-quinolinecarboxylic acid deriv.
• Avdox
• Avolex
• Izilox
• Maxioffoxacin
• Moxeza
• Moxicip
• Moxifloxacine
• Rapiflox
• Vigamox

7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS: 151096-09-2

Formula: C₂₁H₂₄FN₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 401.4314

Ref: IN-DA001N37

Moxifloxacin

CAS: 151096-09-2

Moxifloxacin (Avelox), a 4th-gen fluoroquinolone, fights Gram-positive/negative bacteria and drug-resistant S. pneumoniae.

Formula: C₂₁H₂₄FN₃O₄

Purity: 99.76% - 99.99%

Color and Shape: Almost White Crystalling Power

Molecular weight: 401.43

Ref: TM-T0331L

1-Cyclopropyl-6-Fluoro-7-((4As,7As)-Hexahydro-1H-Pyrrolo[3,4-B]Pyridin-6(2H)-Yl)-8-Methoxy-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid

CAS: 151096-09-2

1-Cyclopropyl-6-Fluoro-7-((4As,7As)-Hexahydro-1H-Pyrrolo[3,4-B]Pyridin-6(2H)-Yl)-8-Methoxy-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid

Purity: 98%

Molecular weight: 401.43g/mol

Ref: 54-PC105083

Moxifloxacin

CAS: 151096-09-2

Moxifloxacin

Formula: C₂₁H₂₄FN₃O₄

Purity: ≥98%

Color and Shape: faint yellow solid

Molecular weight: 401.43g/mol

Ref: 54-BUP17085

Moxifloxacin Hydrochloride Monohydrate

CAS: 151096-09-2, 186826-86-8, 192927-63-2

Formula: C₂₁H₂₄FN₃O₄·HCl·H₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystaline

Molecular weight: 455.92

Ref: 3B-M2479

Moxifloxacin

CAS: 151096-09-2

Applications Moxifloxacin is an antibiotic for the treatment of bacterial infections like bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
References Zhang, H., et al.: Linchuang Junyi Zazhi, 43, 182 (2015); Fernandes, M. J., et al.: Chemosphere, 239, 124729 (2020); Yilancioglu, K., et al.: Sci. Rep., 9, 1 (2019)

Formula: C₂₁H₂₄FN₃O₄

Color and Shape: Neat

Molecular weight: 401.43

Ref: TR-M487460

Moxifloxacin

CAS: 151096-09-2

Inhibitor of DNA synthesis; fluoroquinolone class

Formula: C₂₁H₂₄FN₃O₄

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 401.43 g/mol

Ref: 3D-FM145387

Moxifloxacin

CAS: 151096-09-2

Purity: 98%

Molecular weight: 401.175

Ref: 10-F793005