CAS 15128-82-2

3-Hydroxy-2-nitropyridine

Description:

3-Hydroxy-2-nitropyridine, with the CAS number 15128-82-2, is an organic compound that features a pyridine ring substituted with both a hydroxyl group (-OH) and a nitro group (-NO2). This compound is characterized by its aromatic nature, which contributes to its stability and reactivity. The presence of the hydroxyl group makes it a phenolic compound, potentially enhancing its solubility in polar solvents and influencing its hydrogen bonding capabilities. The nitro group, being an electron-withdrawing substituent, can affect the electronic properties of the pyridine ring, making it more electrophilic. This compound may exhibit biological activity, and its derivatives are often studied for their potential applications in pharmaceuticals and agrochemicals. Additionally, 3-hydroxy-2-nitropyridine can participate in various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions, due to the functional groups present. Safety data should be consulted for handling and storage, as nitro compounds can be sensitive and may pose health risks.

Formula: C₅H₄N₂O₃

InChI: InChI=1S/C5H4N2O3/c8-4-2-1-3-6-5(4)7(9)10/h1-3,8H

InChI key: InChIKey=QBPDSKPWYWIHGA-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C(O)C=CC=N1

Synonyms:

• 2-Nitro-3-hydroxypyridine
• 2-Nitro-3-pyridinol
• 2-Nitropyridin-3-Ol
• 3-Pyridinol, 2-nitro-
• NSC 97501
• 3-Hydroxy-2-nitropyridine

3-Hydroxy-2-nitropyridine

CAS: 15128-82-2

Formula: C₅H₄N₂O₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 140.10

Ref: 3B-H0764

3-Hydroxy-2-nitropyridine, 98%

CAS: 15128-82-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₅H₄N₂O₃

Purity: 98%

Color and Shape: White to yellow or cream, Crystals or powder or crystalline powder

Molecular weight: 140.10

Ref: 02-A14887

3-Pyridinol, 2-nitro-

CAS: 15128-82-2

Formula: C₅H₄N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 140.0969

Ref: IN-DA001N87

3-Hydroxy-2-nitropyridine

CAS: 15128-82-2

3-Hydroxy-2-nitropyridine

Formula: C₅H₄N₂O₃

Purity: 98%

Color and Shape: faint yellow crystalline solid

Molecular weight: 140.10g/mol

Ref: 54-OR5566

3-Hydroxy-2-nitropyridine

CAS: 15128-82-2

Formula: C₅H₄N₂O₃

Molecular weight: 140.10

Ref: 7W-GK2700

3-Hydroxy-2-nitropyridine

CAS: 15128-82-2

Formula: C₅H₄N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 140.098

Ref: 10-F045192

2-Nitro-3-pyridinol

Controlled Product

CAS: 15128-82-2

Applications 2-Nitro-3-pyridinol may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization. It may also be used to prepare (aminoaryl)(benzyloxy)pyridines as potential antitumor agents.
References Gwaltney, S., et al.: Bioorg. Med. Chem. Lett., 11, 1671 (2001); Cui, J., et al.: J. Med. Chem., 54, 6342 (2011)

Formula: C₅H₄N₂O₃

Color and Shape: Neat

Molecular weight: 140.1

Ref: TR-N519930

3-Hydroxy-2-nitropyridine

CAS: 15128-82-2

3-Hydroxy-2-nitropyridine is a chemical compound that has been shown to be an inhibitor of nicotinic acetylcholine receptor. The compound has been found to have luminescence properties and can be used as a fluorescent probe in the study of molecular recognition processes. 3-Hydroxy-2-nitropyridine is also an effective antimicrobial agent and has been shown to have clinical potential for the treatment of neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease. It binds to the nicotinic acetylcholine receptor by forming hydrogen bonds with functional groups on the receptor surface. This binding prevents the agonist from binding and activating the ion channel that leads to depolarization of nerve cells. 3-Hydroxy-2-nitropyridine also reacts with chloride ions in order to form hydrochloric acid, which then inhibits microbial growth by altering their cell membrane permeability. The reaction yield is determined

Formula: C₅H₄N₂O₃

Purity: Min. 95%

Molecular weight: 140.1 g/mol

Ref: 3D-FH00801