Description:2,6-Difluoropyridine is a heterocyclic aromatic compound characterized by a pyridine ring substituted with two fluorine atoms at the 2 and 6 positions. Its molecular formula is C5H4F2N, and it has a molecular weight that reflects the presence of these substituents. This compound is typically a colorless to pale yellow liquid with a distinctive odor. It is known for its moderate polarity and can engage in hydrogen bonding due to the nitrogen atom in the pyridine ring. 2,6-Difluoropyridine is soluble in organic solvents such as ethanol and ether but has limited solubility in water. It is primarily used in the synthesis of pharmaceuticals and agrochemicals, serving as an important building block in various chemical reactions. The presence of fluorine atoms enhances its reactivity and stability, making it valuable in medicinal chemistry. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested.
2,6-Difluoropyridine has been used in the preparation of poly(pyridine ether)s via polycondensation with silylated 1,1,1-tris(4-hydroxyphenyl)ethane. …
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