CAS 151308-34-8

cyclo(gly-asn-trp-his-gly-thr-ala-pro-*B-asp)-thr

Description:

The chemical substance known as cyclo(gly-asn-trp-his-gly-thr-ala-pro-*B-asp)-thr, with the CAS number 151308-34-8, is a cyclic peptide composed of a specific sequence of amino acids. Its structure features a cyclic arrangement, which can enhance stability and bioactivity compared to linear peptides. The presence of various amino acids, including glycine, asparagine, tryptophan, histidine, threonine, alanine, proline, and a modified aspartic acid (*B-asp), suggests potential roles in biological processes, such as signaling or enzyme inhibition. The cyclic nature may contribute to its ability to interact with biological targets, making it of interest in pharmaceutical research. Additionally, the specific sequence and modifications can influence its solubility, binding affinity, and overall pharmacokinetic properties. Such peptides are often studied for their therapeutic potential, including roles in drug design and development, particularly in areas like cancer treatment or neurobiology. Further research would be necessary to elucidate its specific biological functions and applications.

Formula: C₁₀₃H₁₁₅N₂₃O₂₃

InChI: InChI=1/C103H115N23O23/c1-54-102(147)126-35-15-26-83(126)100(145)123-81(46-85(131)110-51-87(133)114-72(90(105)135)45-86(132)115-77(40-60-47-107-69-23-12-9-20-66(60)69)96(141)121-79(43-63-50-106-53-112-63)91(136)111-52-88(134)125-89(55(2)127)101(146)113-54)99(144)120-78(41-61-48-108-70-24-13-10-21-67(61)70)97(142)118-73(36-56-16-5-3-6-17-56)92(137)116-74(37-57-18-7-4-8-19-57)94(139)122-80(44-84(104)130)98(143)119-75(38-58-27-31-64(128)32-28-58)93(138)117-76(39-59-29-33-65(129)34-30-59)95(140)124-82(103(148)149)42-62-49-109-71-25-14-11-22-68(62)71/h3-14,16-25,27-34,47-50,53-55,72-83,89,107-109,127-129H,15,26,35-46,51-52H2,1-2H3,(H2,104,130)(H2,105,135)(H,106,112)(H,110,131)(H,111,136)(H,113,146)(H,114,133)(H,115,132)(H,116,137)(H,117,138)(H,118,142)(H,119,143)(H,120,144)(H,121,141)(H,122,139)(H,123,145)(H,124,140)(H,125,134)(H,148,149)/t54-,55+,72?,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,89-/m0/s1

Synonyms:

• Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH
• (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(3S,6S,12S,15S,26S,29S)-19-carbamoyl-6-[(1R)-1-hydroxyethyl]-12-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-3-methyl-2,5,8,11,14,17,21,24,28-nonaoxo-1,4,7,10,13,16,20,23,27-nonazabicyclo[27.3.0]dotriacontane-26-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]amino]-4-oxo-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
• Res-701-1
• GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP
• RES-701-1 USP/EP/BP
• cyclo(gly-asn-trp-his-gly-thr-ala-pro-*B-asp)-thr
• CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH
• CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP
• L-Tryptophan, glycyl-L-asparaginyl-L-tryptophyl-L-histidylglycyl-L-threonyl-L-alanyl-L-prolyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-phenylalanyl-L-asparaginyl-L-tyrosyl-L-tyrosyl-, (9→1)-lactam
• GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH

Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH

CAS: 151308-34-8

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Formula: C₁₀₃H₁₁₅N₂₃O₂₃

Purity: Min. 95%

Molecular weight: 2,043.16 g/mol

Ref: 3D-FC108692