CAS 151342-35-7

Ro-32-0432

Description:

Ro-32-0432, also known by its CAS number 151342-35-7, is a chemical compound that belongs to the class of selective serotonin reuptake inhibitors (SSRIs). It is primarily researched for its potential applications in the treatment of various psychiatric disorders, particularly depression and anxiety. The compound exhibits a mechanism of action that involves the inhibition of serotonin reuptake, thereby increasing the availability of serotonin in the synaptic cleft, which can enhance mood and emotional well-being. Ro-32-0432 is characterized by its specific binding affinity to serotonin transporters, which distinguishes it from other SSRIs. Additionally, it may possess a favorable side effect profile compared to traditional antidepressants, making it a subject of interest in pharmacological studies. However, as with any pharmaceutical compound, its safety, efficacy, and potential side effects are thoroughly evaluated through clinical trials before it can be approved for widespread use. Further research is ongoing to fully understand its therapeutic potential and mechanisms of action.

Formula: C₂₈H₂₉ClN₄O₂

InChI: InChI=1/C28H28N4O2.ClH/c1-30(2)15-17-10-11-32-20(12-17)13-18-8-9-19(14-24(18)32)25-26(28(34)29-27(25)33)22-16-31(3)23-7-5-4-6-21(22)23;/h4-9,13-14,16-17H,10-12,15H2,1-3H3,(H,29,33,34);1H

InChI key: InChIKey=FXGHOAZJQNLNFD-KRWDZBQOSA-N

SMILES: CN(C)CC1CCn2c(C1)cc1ccc(cc21)C1=C(c2cn(C)c3ccccc23)C(=O)N=C1O.Cl

Synonyms:

• (S)-3-(8-((Dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrol-2,5-dione
• (S)-3-(8-((Dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
• (S)-3-(8-(Dimethylaminomethyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione hydrochloride
• 1H-Pyrrol-2,5-dione, 3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-, (S)-
• 1H-Pyrrole-2,5-dione, 3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-, (S)-
• 1H-Pyrrole-2,5-dione, 3-[(8S)-8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-
• 3-{(8S)-8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
• 3-{8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-3-yl}-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione hydrochloride
• Pyrido[1,2-a]indole, 1H-pyrrole-2,5-dione deriv.
• Ro 32-0432

1H-Pyrrole-2,5-dione, 3-[(8S)-8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-

CAS: 151342-35-7

Formula: C₂₈H₂₈N₄O₂

Color and Shape: Solid

Molecular weight: 452.5475

Ref: IN-DA001NAT

Bisindolylmaleimide XI hydrochloride

CAS: 151342-35-7

Bisindolylmaleimide XI hydrochloride

Molecular weight: 489.01g/mol

Ref: 54-BIMI3192

Ro 32-0432 hydrochloride

CAS: 151342-35-7

Ro 32-0432 is a selective, ATP-competitive, oral pan-PKC inhibitor exhibiting inhibitory effects on PKCα, PKCβI, PKCβII, PKCγ, and PKCε.

Formula: C₂₈H₂₈N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 452.55

Ref: TM-T23244