CAS 15151-57-2

4-Hydroxy-3-nitro-2(1H)-quinolinone

Description:

4-Hydroxy-3-nitro-2(1H)-quinolinone, with the CAS number 15151-57-2, is a chemical compound that belongs to the class of quinolinones, which are heterocyclic aromatic compounds. This substance features a quinoline core structure, characterized by a fused bicyclic system containing a benzene ring and a pyridine ring. The presence of a hydroxyl group (-OH) at the 4-position and a nitro group (-NO2) at the 3-position contributes to its unique chemical properties and reactivity. It is typically a solid at room temperature and may exhibit yellow to orange coloration. The compound is known for its potential applications in various fields, including pharmaceuticals and materials science, due to its ability to form chelates with metal ions and its biological activity. Additionally, it may serve as an intermediate in organic synthesis. As with many nitro compounds, it is important to handle it with care due to potential toxicity and environmental concerns.

Formula: C₉H₆N₂O₄

InChI: InChI=1S/C9H6N2O4/c12-8-5-3-1-2-4-6(5)10-9(13)7(8)11(14)15/h1-4H,(H2,10,12,13)

InChI key: InChIKey=SHZUGBYEPDMAPC-UHFFFAOYSA-N

SMILES: OC=1C=2C(NC(=O)C1N(=O)=O)=CC=CC2

Synonyms:

• 2(1H)-Quinolinone, 4-hydroxy-3-nitro-
• 2,4-Quinolinediol, 3-nitro-
• 2-hydroxy-3-nitroquinolin-4(1H)-one
• 3-Nitro-2,4-Dihydroxyquinoline
• 3-Nitro-2,4-quinolinediol
• 3-Nitroquinoline-2,4-Diol
• 3-Nitroquinoline-2,4-Diol, 4-Hydroxy-3-Nitro-1H-Quinolin-2-One
• 4-hydroxy-3-nitro-2(1H)-Quinolinone
• Timtec-Bb Sbb005381
• 2,4-Dihydroxy-3-nitroquinoline

3-Nitroquinoline-2,4-Diol

CAS: 15151-57-2

3-Nitroquinoline-2,4-Diol

Formula: C₉H₆N₂O₄

Purity: 97%

Molecular weight: 206.15

Ref: 54-OR1011056

2(1H)-Quinolinone, 4-hydroxy-3-nitro-

CAS: 15151-57-2

Formula: C₉H₆N₂O₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 206.1549

Ref: IN-DA007WYC

3-Nitroquinoline-2,4-diol

CAS: 15151-57-2

3-Nitroquinoline-2,4-diol

Formula: C₉H₆N₂O₄

Purity: 98%

Molecular weight: 206.15

Ref: IN-DG32043

4-hydroxy-3-nitro-1,2-dihydroquinolin-2-one

CAS: 15151-57-2

Purity: 96%

Molecular weight: 206.1569977

Ref: 10-F799698

2,4-Dihydroxy-3-nitroquinoline

CAS: 15151-57-2

Formula: C₉H₆N₂O₄

Purity: 96%

Molecular weight: 206.157

Ref: 10-F403624

4-Hydroxy-3-nitro-2(1H)-quinolinone

CAS: 15151-57-2

4-Hydroxy-3-nitro-2(1H)-quinolinone is a quinoline derivative that has been shown to have anticancer activity against cancer cells. It can be used for the treatment of various types of cancer, including lung cancer, breast cancer, and colon cancer. This drug inhibits the growth of cancer cells by blocking the cycle at the G1 phase and inducing apoptosis. It also disrupts mitochondrial membrane potential, leading to an increase in reactive oxygen species and DNA damage. 4-Hydroxy-3-nitro-2(1H)-quinolinone is an epidermal growth factor receptor (EGFR) antagonist and blocks epidermal growth factor signaling through its inhibition of EGFR tyrosine kinase activity. It also downregulates TNFα expression in tumor cells by inhibiting NFκB activation.

Formula: C₉H₆N₂O₄

Purity: Min. 95%

Molecular weight: 206.16 g/mol

Ref: 3D-FH159597