CAS 151602-49-2

5-O-DESMETHYL OMEPRAZOLE

Description:

5-O-Desmethyl omeprazole is a chemical compound that is a derivative of omeprazole, a widely used proton pump inhibitor (PPI) that reduces stomach acid production. This compound is characterized by the absence of a methyl group at the 5-position of the omeprazole structure, which influences its pharmacological properties. It typically appears as a white to off-white solid and is soluble in organic solvents. The compound is of interest in pharmacokinetic studies and metabolic research, as it may serve as a metabolite of omeprazole in biological systems. Its molecular structure includes a benzimidazole ring, which is essential for its activity, and it may exhibit varying degrees of biological activity compared to its parent compound. The CAS number 151602-49-2 uniquely identifies this substance in chemical databases, facilitating research and regulatory processes. Understanding its characteristics is crucial for evaluating its role in drug metabolism and potential therapeutic applications.

Formula: C₁₆H₁₇N₃O₃S

Synonyms:

• 5-Desmethylomeprazole
• 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-5-ol
• 5-O-Desmethyl Omeprazole Discontinued see product # D292120
• 4-Methoxy-2-[[(RS)-(5-hydroxy -1H-benziMidazol-2-yl)sulfinyl]Methyl]-3,5-diMethylpyridine
• Esomeprazole impurity M
• 5-O-Desmethyl OmeprazoleDiscontinued see product # D292120
• Esomeprazol impurity L
• 5-O-DESMETHYL OMEPRAZOLE
• EsoMeprazole sodiuM iMpurity L
• 1H-Benzimidazol-6-ol,2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
• 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-6-ol

1H-Benzimidazol-6-ol, 2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-

CAS: 151602-49-2

Formula: C₁₆H₁₇N₃O₃S

Purity: 97%

Color and Shape: Solid

Molecular weight: 331.3895

Ref: IN-DA001NG8

2-(((4-Methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazol-6-ol

CAS: 151602-49-2

2-(((4-Methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazol-6-ol

Purity: 97%

Molecular weight: 331.4g/mol

Ref: 54-OR1054858

5-O-Desmethyl Omeprazole

CAS: 151602-49-2

Formula: C₁₆H₁₇N₃O₃S

Color and Shape: Off-White Solid

Molecular weight: 331.39

Ref: 4Z-O-025

5-O-Desmethyl Omeprazole

CAS: 151602-49-2

Formula: C₁₆H₁₇N₃O₃S

Color and Shape: Neat

Molecular weight: 331.39

Ref: TR-D292120

5-O-Desmethyl omeprazole

CAS: 151602-49-2

5-O-Desmethyl omeprazole is a benzimidazole compound that inhibits the production of gastric acid. It binds to the H2 receptor, leading to decreased acid secretion. It has been shown to be clinically relevant in patients who are taking clopidogrel and have been found to have low levels of stomach acid. 5-O-Desmethyl omeprazole has also been shown to inhibit the metabolism of clopidogrel and may increase its effect on platelets. 5-O-Desmethyl omeprazole is metabolized by esterases and glucuronidases, which convert it into inactive metabolites. The drug is eliminated unchanged in urine and feces, with a half life of approximately 1 hour.

Formula: C₁₆H₁₇N₃O₃S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 331.39 g/mol

Ref: 3D-FD21303

5-O-Desmethyl Omeprazole

CAS: 151602-49-2

Formula: C₁₆H₁₇N₃O₃S

Molecular weight: 331.39

Ref: ST-EA-CP-O9081