CAS 151729-55-4

C2 Ceramide-1-phosphate

Description:

C2 Ceramide-1-phosphate, also known by its CAS number 151729-55-4, is a bioactive lipid that plays a significant role in cellular signaling and membrane structure. It is a type of ceramide, which is a class of sphingolipids, and is characterized by a long-chain fatty acid linked to a sphingosine backbone. The phosphate group in C2 Ceramide-1-phosphate contributes to its polar nature, making it amphipathic, which allows it to interact with both hydrophilic and hydrophobic environments. This compound is involved in various biological processes, including cell growth, differentiation, and apoptosis. It is also recognized for its role in the regulation of inflammatory responses and cellular stress. Due to its biological significance, C2 Ceramide-1-phosphate is of interest in pharmaceutical and cosmetic formulations, particularly for its potential benefits in skin health and barrier function. Its stability and reactivity can be influenced by environmental factors, making its handling and storage critical in research and application contexts.

Formula: C₂₀H₄₀NO₆P

InChI: InChI=1/C20H40NO6P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(23)19(21-18(2)22)17-27-28(24,25)26/h15-16,19-20,23H,3-14,17H2,1-2H3,(H,21,22)(H2,24,25,26)/b16-15+/t19-,20+/m0/s1

Synonyms:

• N-Acetylsphingosine-1-phosphate
• N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecenyl]Acetamide
• Acetamide, N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]-
• (2S,3R,E)-2-acetamido-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
• C2 Ceramide-1-phosphate

C2 Ceramide-1-phosphate

Controlled Product

CAS: 151729-55-4

Applications Ceramide-1-phosphate blocks apoptosis through inhibition of acid sphingomyelinase in macrophages.
References Furukawa, A., et al.: Mol. Cell. Biochem., 305, 27 (2007), Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009),

Formula: C₂₀H₄₀NO₆P

Color and Shape: Neat

Molecular weight: 421.51

Ref: TR-C262710