CAS 15176-29-1

5-ethyl-2'-deoxyuridine

Description:

5-Ethyl-2'-deoxyuridine is a nucleoside analog that features an ethyl group at the 5-position of the uracil base, which is attached to a deoxyribose sugar. This compound is structurally similar to thymidine, differing primarily by the presence of the ethyl substituent. It is characterized by its ability to incorporate into DNA during replication, potentially affecting nucleic acid synthesis and function. The presence of the ethyl group can influence its biological activity, making it of interest in research related to antiviral and anticancer therapies. 5-Ethyl-2'-deoxyuridine is typically studied for its effects on cellular processes and its potential as a therapeutic agent. Its solubility, stability, and reactivity can vary depending on the conditions, such as pH and temperature. As a nucleoside analog, it may also exhibit interactions with various enzymes involved in nucleotide metabolism, which can be significant in understanding its pharmacological properties and mechanisms of action.

Formula: C₁₁H₁₆N₂O₅

InChI: InChI=1/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)/t7-,8+,9+/m0/s1

InChI key: InChIKey=XACKNLSZYYIACO-DJLDLDEBSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(CC)C(=O)N1

Synonyms:

• 1-(2-deoxypentofuranosyl)-5-ethylpyrimidine-2,4(1H,3H)-dione
• 2'-Deoxy-5-Ethyluridine
• 5-Ethyl-1-(2′-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)uracil
• 5-Ethyldeoxyuridine
• 5-ethyl-1-[4-hydroxy-3-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione
• Aedurid
• Edoxudine
• Epoxudine
• Orf 15817
• Rwj 15817
• Uridine, 2′-deoxy-5-ethyl-
• β-5-Ethyl-2′-deoxyuridine
• β-5-Ethyldeoxyuridine
• 5-Ethyl-2′-deoxyuridine
• Aids021723
• Etudr
• 5-ETHYL-2'-DEOXYURIDINE USP/EP/BP
• edoxudin
• 5-Ethyl-durd
• edu
• beta-5-ethyldeoxyuridine
• 2’-deoxy-5-ethyl-uridin
• EUdR
• Aids-021723

5-Ethyl-2'-deoxyuridine

CAS: 15176-29-1

Formula: C₁₁H₁₆N₂O₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 256.2551

Ref: IN-DA00AOPE

5-Ethyl-2''-deoxyuridine

CAS: 15176-29-1

Formula: C₁₁H₁₆N₂O₅

Molecular weight: 256.26

Ref: 7W-GN0375

Edoxudine

CAS: 15176-29-1

Edoxudine

Purity: ≥98%

Molecular weight: 256.26g/mol

Ref: 54-BUP11248

Edoxudine

CAS: 15176-29-1

Edoxudine, a thymidine analog, combats herpes simplex and modulates 5-fluorouracil, boosting its effectiveness and safety.

Formula: C₁₁H₁₆N₂O₅

Purity: 99.94%

Color and Shape: Solid

Molecular weight: 256.26

Ref: TM-T4374

5-Ethyl-2'-deoxyuridine

CAS: 15176-29-1

Applications 5-Ethyl-2’-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use.
References Kralovanszky, J., et al.: J. Cancer. Res. Clin. Oncol., 125, 675 (1999); Jeney, A., et al.: Eur. J. Cancer. Clin. Oncol., 22, 557 (1986);

Formula: C₁₁H₁₆N₂O₅

Color and Shape: Beige

Molecular weight: 256.2551

Ref: TR-E915020

2'-Deoxy-5-ethyluridine

CAS: 15176-29-1

2'-Deoxy-5-ethyluridine is a nucleoside analog that is used in cancer gene therapy. It is an analog of the natural pyrimidine base uracil and inhibits RNA synthesis by competing with natural nucleosides for incorporation into the growing RNA chain. 2'-Deoxy-5-ethyluridine is cytotoxic to cervical cancer cells, inhibiting cell growth and proliferation at inhibitory doses of 0.1 μM. This drug has also been shown to have synergistic effects with other drugs such as trifluoroacetic acid, monoclonal antibody, tissue culture, glycosidic bond, biological properties, cancer tissues, and polymerase chain reaction (PCR).

Formula: C₁₁H₁₆N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 256.26 g/mol

Ref: 3D-ND08006

5-Ethyl-2’-deoxyuridine-d5

Controlled Product

CAS: 15176-29-1

Applications Isotope labelled 5-Ethyl-2’-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use.
References Kralovanszky, J., et al.: J. Cancer. Res. Clin. Oncol., 125, 675 (1999); Jeney, A., et al.: Eur. J. Cancer. Clin. Oncol., 22, 557 (1986);

Formula: C₁₁D₅H₁₁N₂O₅

Color and Shape: Neat

Molecular weight: 261.286

Ref: TR-E915022