CAS 151767-03-2

2(1H)-Pyrimidinone, 1-[2-[(acetyloxy)methyl]-1,3-oxathiolan-5-yl]-4-amino-, cis-

Description:

2(1H)-Pyrimidinone, 1-[2-[(acetyloxy)methyl]-1,3-oxathiolan-5-yl]-4-amino-, cis- (CAS 151767-03-2) is a chemical compound characterized by its pyrimidinone core structure, which features a pyrimidine ring with a carbonyl group and an amino group at specific positions. The presence of the oxathiolane moiety indicates that it contains a five-membered ring with sulfur and oxygen, contributing to its unique reactivity and potential biological activity. The acetyloxy group suggests that the compound may undergo hydrolysis or other transformations, influencing its pharmacokinetic properties. This compound may exhibit various properties such as solubility in polar solvents, potential for hydrogen bonding due to the amino and carbonyl groups, and possible interactions with biological targets, making it of interest in medicinal chemistry. Its stereochemistry, indicated by the "cis-" designation, may also play a crucial role in its biological activity and interactions. Overall, this compound's structural features suggest potential applications in pharmaceuticals or as a biochemical probe.

Formula: C₁₀H₁₃N₃O₄S

InChI: InChI=1/C10H13N3O4S/c1-6(14)16-4-9-17-8(5-18-9)13-3-2-7(11)12-10(13)15/h2-3,8-9H,4-5H2,1H3,(H2,11,12,15)/t8-,9+/s2

InChI key: InChIKey=GOKJDGDJMGPXQO-BRJQIKQINA-N

SMILES: O=C1N([C@H]2O[C@@H](COC(C)=O)SC2)C=CC(N)=N1

Synonyms:

• 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
• 2(1H)-Pyrimidinone, 1-[2-[(acetyloxy)methyl]-1,3-oxathiolan-5-yl]-4-amino-, cis-(±)-
• 2(1H)-Pyrimidinone, 1-[2-[(acetyloxy)methyl]-1,3-oxathiolan-5-yl]-4-amino-, cis-
• 2(1H)-Pyrimidinone, 1-[2-[(acetyloxy)methyl]-1,3-oxathiolan-5-yl]-4-amino-, cis- (9CI)
• 5'-O-Acetyllamivudine

5'-O-Acetyllamivudine

CAS: 151767-03-2

5'-O-Acetyllamivudine is an antiviral agent that has been shown to have antiretroviral activity against HIV-1 and influenza A virus. It is a nucleoside analog that inhibits the synthesis of viral DNA by competitively inhibiting the enzyme DNA polymerase. 5'-O-Acetyllamivudine is also used as an anticancer drug, which may be due to its ability to inhibit DNA replication in tumor cells.

Formula: C₁₀H₁₃N₃O₄S

Purity: Min. 95%

Molecular weight: 271.29 g/mol

Ref: 3D-NA15183